Phenotype calls
Associations between mutant genotypes and their observed phenotypes are recorded in the ‘genotype-phenotype’ data core. This dataset is closely related to the ‘statistical-result’ dataset, but it can be seen as a convenient way to capture the set of phenotype hits following statistical analysis.
Some fields relevant to the ‘genotype-phenotype’ core are provided in the table below.
| Field name | Description |
|---|---|
| marker_symbol | Mouse gene identifier in symbol format, e.g. Car4 |
| marker_accession_id | Mouse gene identifier in MGI id format, e.g. MGI:1096574 |
| zygosity | Zygosity of the mutant specimens |
| parameter_stable_id | Identifier for phenotyping parameter |
| sex | Sex of the mutant specimens |
| mp_term_id | Identifier of a mammalian phenotype |
Several other fields are also available; a complete list of available parameters is available here.
Example – phenotypes for a gene symbol
Query criteria:
Marker symbol: Car4
Query URL:
https://www.ebi.ac.uk/mi/impc/solr/genotype-phenotype/select?q=marker_symbol:Car4Example – phenotypes for a parameter
Query criteria:
Parameter identifier: IMPC_ECG_004_001 (RR interval)
Query URL:
https://www.ebi.ac.uk/mi/impc/solr/genotype-phenotype/select?q=parameter_stable_id:IMPC_ECG_004_001