A Clinical Chemistry phenotypic assay was performed on 1674 mice. The charts show the results of measuring Sodium in 6 female, 8 male mutants compared to 841 female, 819 male controls. The mutants are for the Pightm1.1(KOMP)Vlcg allele.
increased circulating sodium level
Loading data
P-values equal or lower to 10-4 (P < 0.0001) are marked as significant.
Sodium | JAX | Pightm1.1(KOMP)Vlcg | heterozygote | Early adult | JR18614 | 9.46x10-4 | 5.2x10-4 | 5.29x10-6 |
Pigh data charts
SodiumExperiments performed
Associated phenotype
Zygosity
heterozygote
Testing protocol
Measured value
Sodium
Testing environment
Lab conditions and equipment
Life stage
Early adult
Background Strain
involves: C57BL/6NJ
Phenotyping center
JAX
* The high throughput nature of the IMPC means that large control sample sizes may accumulate over a long period of time. See the animal welfare guidelines for more information.
Sodium / Box plot
Sodium / Scatter plot
Results of statistical analysis
Genotype P value
5.29x10-6
Genotype*Female P value
5.2x10-4
Genotype*Male P value
9.46x10-4
Classification
With phenotype threshold value 1e-04 - both sexes equally
Summary statistics of all data in the dataset
Statistical method
Batch effect significant | true |
Variance significant | true |
Genotype*Sex interaction effect p value | 5.29x10-6 |
Genotype parameter estimate | 1.801 |
Genotype standard error estimate | 0.448 |
Genotype Effect P Value | 5.29x10-6 |
Sex Parameter Estimate | 1.801 |
Sex Standard Error Estimate | 0.128 |
Sex Effect P Value | 5.29x10-6 |
Intercept Estimate | 147.364 |
Intercept Estimate Standard Error | 0.287 |
Sex Male KO P Value | 5.29x10-6 |
Sex Female KO P Value | 5.29x10-6 |
WT Residuals Normality Tests | 5.96x10-1 |
KO Residuals Normality Tests | 4.99x10-1 |
Statistical analysis API access
Experimental data download
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