A Plasma Chemistry phenotypic assay was performed on 597 mice. The charts show the results of measuring HDL cholesterol in 6 female, 6 male mutants compared to 294 female, 291 male controls. The mutants are for the Pightm1.1(KOMP)Vlcg allele.
decreased circulating HDL cholesterol level
Loading data
P-values equal or lower to 10-4 (P < 0.0001) are marked as significant.
HDL cholesterol | JAX | Pightm1.1(KOMP)Vlcg | heterozygote | Early adult | JR18614 | 3.29x10-5 | 3.48x10-1 | 3.48x10-1 |
Pigh data charts
HDL cholesterolExperiments performed
Associated phenotype
Zygosity
heterozygote
Testing protocol
Measured value
HDL cholesterol
Testing environment
Lab conditions and equipment
Life stage
Early adult
Background Strain
involves: C57BL/6NJ
Phenotyping center
JAX
* The high throughput nature of the IMPC means that large control sample sizes may accumulate over a long period of time. See the animal welfare guidelines for more information.
HDL cholesterol / Box plot
HDL cholesterol / Scatter plot
Results of statistical analysis
Genotype P value
3.48x10-1
Genotype*Female P value
3.48x10-1
Genotype*Male P value
3.29x10-5
Classification
Overally insignificant [level = 1e-04 , pvalue = 0.347656497219601 ]; but with phenotype threshold value 1e-04 - males only
Summary statistics of all data in the dataset
Statistical method
Batch effect significant | true |
Variance significant | true |
Genotype*Sex interaction effect p value | 3.48x10-1 |
Genotype parameter estimate | 17.625 |
Genotype standard error estimate | 3.770 |
Genotype Effect P Value | 3.48x10-1 |
Sex Parameter Estimate | 17.625 |
Sex Standard Error Estimate | 1.367 |
Sex Effect P Value | 3.48x10-1 |
Intercept Estimate | 23.957 |
Intercept Estimate Standard Error | 5.509 |
Sex Male KO P Value | 3.48x10-1 |
Sex Female KO P Value | 3.48x10-1 |
WT Residuals Normality Tests | 1.93x10-7 |
KO Residuals Normality Tests | 7.09x10-1 |
Statistical analysis API access
Experimental data download
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