decreased circulating HDL cholesterol level

  Loading data
P-values equal or lower to 10-4 (P < 0.0001) are marked as significant.
HDL cholesterolJAXPightm1.1(KOMP)VlcgheterozygoteEarly adultJR186143.29x10-53.48x10-13.48x10-1

Pigh data charts

HDL cholesterol
Combination tested with the lowest p-value of 3.29x10-5
Experiments performed

A Plasma Chemistry phenotypic assay was performed on 597 mice. The charts show the results of measuring HDL cholesterol in 6 female, 6 male mutants compared to 294 female, 291 male controls. The mutants are for the Pightm1.1(KOMP)Vlcg allele.

Associated phenotype
Zygosity
heterozygote
Testing protocol
Measured value
HDL cholesterol
Testing environment
Lab conditions and equipment
Life stage
Early adult
Background Strain
involves: C57BL/6NJ
Phenotyping center
JAX

* The high throughput nature of the IMPC means that large control sample sizes may accumulate over a long period of time. See the animal welfare guidelines for more information.

HDL cholesterol / Box plot
HDL cholesterol / Scatter plot

Results of statistical analysis

Summary statistics of all data in the dataset

Statistical method

Batch effect significant true
Variance significant true
Genotype*Sex interaction effect p value 3.48x10-1
Genotype parameter estimate 17.625
Genotype standard error estimate 3.770
Genotype Effect P Value 3.48x10-1
Sex Parameter Estimate 17.625
Sex Standard Error Estimate 1.367
Sex Effect P Value 3.48x10-1
Intercept Estimate 23.957
Intercept Estimate Standard Error 5.509
Sex Male KO P Value 3.48x10-1
Sex Female KO P Value 3.48x10-1
WT Residuals Normality Tests 1.93x10-7
KO Residuals Normality Tests 7.09x10-1

Windowing parameters

View documentation about soft windowing
Sharpness (k) 8.324
Bandwidth (l)40

Experimental data download

Download data as:  

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