decreased prepulse inhibition

  Loading data
P-values equal or lower to 10-4 (P < 0.0001) are marked as significant.
% Pre-pulse inhibition - PPI4TCPEprs1tm1b(EUCOMM)HmguheterozygoteEarly adultTCPA0537Cre1.9x10-41.95x10-24.01x10-5

Eprs1 data charts

% Pre-pulse inhibition - PPI4
Combination tested with the lowest p-value of 4.01x10-5
Experiments performed

A Acoustic Startle and Pre-pulse Inhibition (PPI) phenotypic assay was performed on 1600 mice. The charts show the results of measuring % Pre-pulse inhibition - PPI4 in 8 female, 8 male mutants compared to 813 female, 771 male controls. The mutants are for the Eprs1tm1b(EUCOMM)Hmgu allele.

Associated phenotype
Zygosity
heterozygote
Testing protocol
Measured value
% Pre-pulse inhibition - PPI4
Testing environment
Lab conditions and equipment
Life stage
Early adult
Background Strain
involves: C57BL/6NCrl
Phenotyping center
TCP

* The high throughput nature of the IMPC means that large control sample sizes may accumulate over a long period of time. See the animal welfare guidelines for more information.

Statistical information

Batch effect significant true
Variance significant true
Genotype*Sex interaction effect p value 4.01x10-5
Genotype parameter estimate 3.971
Genotype standard error estimate 3.643
Genotype Effect P Value 4.01x10-5
Sex Parameter Estimate 3.971
Sex Standard Error Estimate 1.393
Sex Effect P Value 4.01x10-5
Intercept Estimate 89.142
Intercept Estimate Standard Error 4.437
Sex Male KO P Value 4.01x10-5
Sex Female KO P Value 4.01x10-5
WT Residuals Normality Tests 1.13x10-33
KO Residuals Normality Tests 7.05x10-2

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