A Acoustic Startle and Pre-pulse Inhibition (PPI) phenotypic assay was performed on 1600 mice. The charts show the results of measuring % Pre-pulse inhibition - PPI4 in 8 female, 8 male mutants compared to 813 female, 771 male controls. The mutants are for the Eprs1tm1b(EUCOMM)Hmgu allele.
decreased prepulse inhibition
Loading data
P-values equal or lower to 10-4 (P < 0.0001) are marked as significant.
% Pre-pulse inhibition - PPI4 | TCP | Eprs1tm1b(EUCOMM)Hmgu | heterozygote | Early adult | TCPA0537Cre | 1.9x10-4 | 1.95x10-2 | 4.01x10-5 |
Eprs1 data charts
% Pre-pulse inhibition - PPI4Experiments performed
Associated phenotype
Zygosity
heterozygote
Testing protocol
Measured value
% Pre-pulse inhibition - PPI4
Testing environment
Lab conditions and equipment
Life stage
Early adult
Background Strain
involves: C57BL/6NCrl
Phenotyping center
TCP
* The high throughput nature of the IMPC means that large control sample sizes may accumulate over a long period of time. See the animal welfare guidelines for more information.
Statistical information
Batch effect significant | true |
Variance significant | true |
Genotype*Sex interaction effect p value | 4.01x10-5 |
Genotype parameter estimate | 3.971 |
Genotype standard error estimate | 3.643 |
Genotype Effect P Value | 4.01x10-5 |
Sex Parameter Estimate | 3.971 |
Sex Standard Error Estimate | 1.393 |
Sex Effect P Value | 4.01x10-5 |
Intercept Estimate | 89.142 |
Intercept Estimate Standard Error | 4.437 |
Sex Male KO P Value | 4.01x10-5 |
Sex Female KO P Value | 4.01x10-5 |
WT Residuals Normality Tests | 1.13x10-33 |
KO Residuals Normality Tests | 7.05x10-2 |