A Body Composition (DEXA lean/fat) phenotypic assay was performed on 5203 mice. The charts show the results of measuring BMC/Body weight in 8 female, 8 male mutants compared to 2622 female, 2565 male controls. The mutants are for the Serpinb2tm1b(EUCOMM)Wtsi allele.
decreased bone mineral content
Loading data
P-values equal or lower to 10-4 (P < 0.0001) are marked as significant.
| BMC/Body weight | JAX | Serpinb2tm1b(EUCOMM)Wtsi | homozygote | Early adult | JR28793 | 6.17x10-4 | 1.4x10-2 | 9.18x10-5 | |
Serpinb2 data charts
BMC/Body weightExperiments performed
Associated phenotype
Zygosity
homozygote
Testing protocol
Measured value
BMC/Body weight
Testing environment
Lab conditions and equipment
Life stage
Early adult
Background Strain
involves: C57BL/6NJ
Phenotyping center
JAX
* The high throughput nature of the IMPC means that large control sample sizes may accumulate over a long period of time. See the animal welfare guidelines for more information.
BMC/Body weight / Box plot
BMC/Body weight / Scatter plot
Results of statistical analysis
Genotype P value
9.18x10-5
Genotype*Female P value
1.4x10-2
Genotype*Male P value
6.17x10-4
Classification
With phenotype threshold value 1e-04 - both sexes equally
Summary statistics of all data in the dataset
Statistical method
| Batch effect significant | true |
| Variance significant | true |
| Genotype*Sex interaction effect p value | 9.18x10-5 |
| Genotype parameter estimate | -0.003 |
| Genotype standard error estimate | 0.000 |
| Genotype Effect P Value | 9.18x10-5 |
| Sex Parameter Estimate | -0.003 |
| Sex Standard Error Estimate | 0.000 |
| Sex Effect P Value | 9.18x10-5 |
| Intercept Estimate | 0.019 |
| Intercept Estimate Standard Error | 0.000 |
| Sex Male KO P Value | 9.18x10-5 |
| Sex Female KO P Value | 9.18x10-5 |
| WT Residuals Normality Tests | 1.42x10-6 |
| KO Residuals Normality Tests | 1.63x10-1 |
Statistical analysis API access
Experimental data download
Download data as: