A Open Field - centre start phenotypic assay was performed on 4073 mice. The charts show the results of measuring Center average speed in 8 female, 8 male mutants compared to 2036 female, 2021 male controls. The mutants are for the Serpinb2tm1b(EUCOMM)Wtsi allele.
hyperactivity
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P-values equal or lower to 10-4 (P < 0.0001) are marked as significant.
Center average speed | JAX | Serpinb2tm1b(EUCOMM)Wtsi | homozygote | Early adult | JR28793 | 6.93x10-1 | 9x10-6 | 9x10-6 |
Serpinb2 data charts
Center average speedExperiments performed
Associated phenotype
Zygosity
homozygote
Testing protocol
Measured value
Center average speed
Testing environment
Lab conditions and equipment
Life stage
Early adult
Background Strain
involves: C57BL/6NJ
Phenotyping center
JAX
* The high throughput nature of the IMPC means that large control sample sizes may accumulate over a long period of time. See the animal welfare guidelines for more information.
Center average speed / Box plot
Center average speed / Scatter plot
Results of statistical analysis
Genotype P value
9x10-6
Genotype*Female P value
9x10-6
Genotype*Male P value
6.93x10-1
Classification
Overally significant [level = 1e-04 , pvalue = 9.00182464591559e-06 ]; and with phenotype threshold value 1e-04 - females only
Summary statistics of all data in the dataset
Statistical method
Batch effect significant | true |
Variance significant | true |
Genotype*Sex interaction effect p value | 9x10-6 |
Genotype parameter estimate | -0.516 |
Genotype standard error estimate | 0.482 |
Genotype Effect P Value | 9x10-6 |
Sex Parameter Estimate | -0.516 |
Sex Standard Error Estimate | 0.062 |
Sex Effect P Value | 9x10-6 |
Intercept Estimate | 4.014 |
Intercept Estimate Standard Error | 0.198 |
Sex Male KO P Value | 9x10-6 |
Sex Female KO P Value | 9x10-6 |
WT Residuals Normality Tests | 9.16x10-31 |
KO Residuals Normality Tests | 5.78x10-1 |
Statistical analysis API access
Experimental data download
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