hyperactivity

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P-values equal or lower to 10-4 (P < 0.0001) are marked as significant.
Center average speedJAXSerpinb2tm1b(EUCOMM)WtsihomozygoteEarly adultJR287936.93x10-19x10-69x10-6

Serpinb2 data charts

Center average speed
Combination tested with the lowest p-value of 9x10-6
Experiments performed

A Open Field - centre start phenotypic assay was performed on 4073 mice. The charts show the results of measuring Center average speed in 8 female, 8 male mutants compared to 2036 female, 2021 male controls. The mutants are for the Serpinb2tm1b(EUCOMM)Wtsi allele.

Associated phenotype
Zygosity
homozygote
Testing protocol
Measured value
Center average speed
Testing environment
Lab conditions and equipment
Life stage
Early adult
Background Strain
involves: C57BL/6NJ
Phenotyping center
JAX

* The high throughput nature of the IMPC means that large control sample sizes may accumulate over a long period of time. See the animal welfare guidelines for more information.

Center average speed / Box plot
Center average speed / Scatter plot

Results of statistical analysis

Summary statistics of all data in the dataset

Statistical method

Batch effect significant true
Variance significant true
Genotype*Sex interaction effect p value 9x10-6
Genotype parameter estimate -0.516
Genotype standard error estimate 0.482
Genotype Effect P Value 9x10-6
Sex Parameter Estimate -0.516
Sex Standard Error Estimate 0.062
Sex Effect P Value 9x10-6
Intercept Estimate 4.014
Intercept Estimate Standard Error 0.198
Sex Male KO P Value 9x10-6
Sex Female KO P Value 9x10-6
WT Residuals Normality Tests 9.16x10-31
KO Residuals Normality Tests 5.78x10-1

Windowing parameters

View documentation about soft windowing
Sharpness (k) 5.426
Bandwidth (l)1558

Experimental data download

Download data as:  

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