increased circulating potassium level

  Loading data
P-values equal or lower to 10-4 (P < 0.0001) are marked as significant.
PotassiumMRC HarwellNkx2-6em1(IMPC)HhomozygoteEarly adultH-Nkx2-6-DEL5-EM1-B6N9.69x10-43.71x10-53.54x10-6

Nkx2-6 data charts

Potassium
Combination tested with the lowest p-value of 3.54x10-6
Experiments performed

A Clinical Chemistry phenotypic assay was performed on 4424 mice. The charts show the results of measuring Potassium in 6 female, 8 male mutants compared to 2216 female, 2194 male controls. The mutants are for the Nkx2-6em1(IMPC)H allele.

Associated phenotype
Zygosity
homozygote
Testing protocol
Measured value
Potassium
Testing environment
Lab conditions and equipment
Life stage
Early adult
Background Strain
involves: C57BL/6NTac
Phenotyping center
MRC Harwell

* The high throughput nature of the IMPC means that large control sample sizes may accumulate over a long period of time. See the animal welfare guidelines for more information.

Potassium / Box plot
Potassium / Scatter plot

Results of statistical analysis

Summary statistics of all data in the dataset

Statistical method

Batch effect significant true
Variance significant true
Genotype*Sex interaction effect p value 3.54x10-6
Genotype parameter estimate 0.398
Genotype standard error estimate 0.135
Genotype Effect P Value 3.54x10-6
Sex Parameter Estimate 0.398
Sex Standard Error Estimate 0.061
Sex Effect P Value 3.54x10-6
Intercept Estimate 3.884
Intercept Estimate Standard Error 0.047
Sex Male KO P Value 3.54x10-6
Sex Female KO P Value 3.54x10-6
WT Residuals Normality Tests 2.04x10-6
KO Residuals Normality Tests 4.94x10-1

Windowing parameters

View documentation about soft windowing
Sharpness (k) 2.305
Bandwidth (l)419

Experimental data download

Download data as:  

The IMPC Newsletter

Get highlights of the most important data releases, news and events, delivered straight to your email inbox

Subscribe to newsletter