A Clinical Chemistry phenotypic assay was performed on 4424 mice. The charts show the results of measuring Potassium in 6 female, 8 male mutants compared to 2216 female, 2194 male controls. The mutants are for the Nkx2-6em1(IMPC)H allele.
increased circulating potassium level
Loading data
P-values equal or lower to 10-4 (P < 0.0001) are marked as significant.
Potassium | MRC Harwell | Nkx2-6em1(IMPC)H | homozygote | Early adult | H-Nkx2-6-DEL5-EM1-B6N | 9.69x10-4 | 3.71x10-5 | 3.54x10-6 |
Nkx2-6 data charts
PotassiumExperiments performed
Associated phenotype
Zygosity
homozygote
Testing protocol
Measured value
Potassium
Testing environment
Lab conditions and equipment
Life stage
Early adult
Background Strain
involves: C57BL/6NTac
Phenotyping center
MRC Harwell
* The high throughput nature of the IMPC means that large control sample sizes may accumulate over a long period of time. See the animal welfare guidelines for more information.
Potassium / Box plot
Potassium / Scatter plot
Results of statistical analysis
Genotype P value
3.54x10-6
Genotype*Female P value
3.71x10-5
Genotype*Male P value
9.69x10-4
Classification
With phenotype threshold value 1e-04 - both sexes equally
Summary statistics of all data in the dataset
Statistical method
Batch effect significant | true |
Variance significant | true |
Genotype*Sex interaction effect p value | 3.54x10-6 |
Genotype parameter estimate | 0.398 |
Genotype standard error estimate | 0.135 |
Genotype Effect P Value | 3.54x10-6 |
Sex Parameter Estimate | 0.398 |
Sex Standard Error Estimate | 0.061 |
Sex Effect P Value | 3.54x10-6 |
Intercept Estimate | 3.884 |
Intercept Estimate Standard Error | 0.047 |
Sex Male KO P Value | 3.54x10-6 |
Sex Female KO P Value | 3.54x10-6 |
WT Residuals Normality Tests | 2.04x10-6 |
KO Residuals Normality Tests | 4.94x10-1 |
Statistical analysis API access
Experimental data download
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