Intraperitoneal glucose tolerance test

  Loading data
P-values equal or lower to 10-4 (P < 0.0001) are marked as significant.
Initial response to glucose challengeICSLmnatm1b(EUCOMM)WtsiheterozygoteEarly adultIP00005431a2.85x10-6

Lmna data charts

Initial response to glucose challenge
Combination tested with the lowest p-value of 2.85x10-6
Experiments performed

A Intraperitoneal glucose tolerance test (IPGTT) phenotypic assay was performed on 1719 mice. The charts show the results of measuring Initial response to glucose challenge in 3 female, 8 male mutants compared to 843 female, 865 male controls. The mutants are for the Lmnatm1b(EUCOMM)Wtsi allele.

Associated phenotype
Zygosity
heterozygote
Testing protocol
Measured value
Initial response to glucose challenge
Testing environment
Lab conditions and equipment
Life stage
Early adult
Background Strain
involves: C57BL/6N
Phenotyping center
ICS

* The high throughput nature of the IMPC means that large control sample sizes may accumulate over a long period of time. See the animal welfare guidelines for more information.

Initial response to glucose challenge / Box plot
Initial response to glucose challenge / Scatter plot

Results of statistical analysis

Summary statistics of all data in the dataset

Statistical method

Batch effect significant false
Variance significant true
Genotype*Sex interaction effect p value 2.85x10-6
Genotype parameter estimate N/A
Genotype standard error estimate 15.474
Genotype Effect P Value 2.85x10-6
Sex Parameter Estimate N/A
Sex Standard Error Estimate N/A
Sex Effect P Value 2.85x10-6
Intercept Estimate 218.915
Intercept Estimate Standard Error 3.227
Sex Male KO P Value 2.85x10-6
Sex Female KO P Value 2.85x10-6
WT Residuals Normality Tests 5.5x10-1
KO Residuals Normality Tests 1.65x10-1

Windowing parameters

View documentation about soft windowing
Sharpness (k) 8.324
Bandwidth (l)180

Experimental data download

Download data as:  

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