A Intraperitoneal glucose tolerance test (IPGTT) phenotypic assay was performed on 1719 mice. The charts show the results of measuring Initial response to glucose challenge in 3 female, 8 male mutants compared to 843 female, 865 male controls. The mutants are for the Lmnatm1b(EUCOMM)Wtsi allele.
Intraperitoneal glucose tolerance test
Loading data
P-values equal or lower to 10-4 (P < 0.0001) are marked as significant.
Initial response to glucose challenge | ICS | Lmnatm1b(EUCOMM)Wtsi | heterozygote | Early adult | IP00005431a | 2.85x10-6 | — | — |
Lmna data charts
Initial response to glucose challengeExperiments performed
Associated phenotype
Zygosity
heterozygote
Testing protocol
Measured value
Initial response to glucose challenge
Testing environment
Lab conditions and equipment
Life stage
Early adult
Background Strain
involves: C57BL/6N
Phenotyping center
ICS
* The high throughput nature of the IMPC means that large control sample sizes may accumulate over a long period of time. See the animal welfare guidelines for more information.
Initial response to glucose challenge / Box plot
Initial response to glucose challenge / Scatter plot
Results of statistical analysis
Genotype P value
2.85x10-6
Genotype*Female P value
N/A
Genotype*Male P value
N/A
Classification
With phenotype threshold value 1e-04 - a significant change for the one sex (male) tested
Summary statistics of all data in the dataset
Statistical method
Batch effect significant | false |
Variance significant | true |
Genotype*Sex interaction effect p value | 2.85x10-6 |
Genotype parameter estimate | N/A |
Genotype standard error estimate | 15.474 |
Genotype Effect P Value | 2.85x10-6 |
Sex Parameter Estimate | N/A |
Sex Standard Error Estimate | N/A |
Sex Effect P Value | 2.85x10-6 |
Intercept Estimate | 218.915 |
Intercept Estimate Standard Error | 3.227 |
Sex Male KO P Value | 2.85x10-6 |
Sex Female KO P Value | 2.85x10-6 |
WT Residuals Normality Tests | 5.5x10-1 |
KO Residuals Normality Tests | 1.65x10-1 |
Statistical analysis API access
Experimental data download
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