A X-ray phenotypic assay was performed on 877 mice. The charts show the results of measuring Tibia length in 5 female, 5 male mutants compared to 424 female, 443 male controls. The mutants are for the Lmnatm1b(EUCOMM)Wtsi allele.
short tibia
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P-values equal or lower to 10-4 (P < 0.0001) are marked as significant.
| Tibia length | ICS | Lmnatm1b(EUCOMM)Wtsi | heterozygote | Early adult | IP00005431a | 1.39x10-4 | 2.64x10-3 | 2.33x10-5 | |
Lmna data charts
Tibia lengthExperiments performed
Associated phenotype
Zygosity
heterozygote
Testing protocol
Measured value
Tibia length
Testing environment
Lab conditions and equipment
Life stage
Early adult
Background Strain
involves: C57BL/6N
Phenotyping center
ICS
* The high throughput nature of the IMPC means that large control sample sizes may accumulate over a long period of time. See the animal welfare guidelines for more information.
Tibia length / Box plot
Tibia length / Scatter plot
Results of statistical analysis
Genotype P value
2.33x10-5
Genotype*Female P value
2.64x10-3
Genotype*Male P value
1.39x10-4
Classification
With phenotype threshold value 1e-04 - both sexes equally
Summary statistics of all data in the dataset
Statistical method
| Batch effect significant | true |
| Variance significant | true |
| Genotype*Sex interaction effect p value | 2.33x10-5 |
| Genotype parameter estimate | -0.116 |
| Genotype standard error estimate | 0.084 |
| Genotype Effect P Value | 2.33x10-5 |
| Sex Parameter Estimate | -0.116 |
| Sex Standard Error Estimate | 0.024 |
| Sex Effect P Value | 2.33x10-5 |
| Intercept Estimate | 15.951 |
| Intercept Estimate Standard Error | 0.107 |
| Sex Male KO P Value | 2.33x10-5 |
| Sex Female KO P Value | 2.33x10-5 |
| WT Residuals Normality Tests | 1.77x10-7 |
| KO Residuals Normality Tests | 4.73x10-1 |
Statistical analysis API access
Experimental data download
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