decreased total body fat amount

  Loading data
P-values equal or lower to 10-4 (P < 0.0001) are marked as significant.
Fat MassWTSILdhatm1a(EUCOMM)WtsiheterozygoteEarly adultEPD0070_2_G041.4x10-76.25x10-26.25x10-2

Ldha data charts

Fat Mass
Combination tested with the lowest p-value of 1.4x10-7
Experiments performed

A Dexa-scan analysis phenotypic assay was performed on 1610 mice. The charts show the results of measuring Fat Mass in 8 female, 8 male mutants compared to 778 female, 816 male controls. The mutants are for the Ldhatm1a(EUCOMM)Wtsi allele.

Associated phenotype
Zygosity
heterozygote
Testing protocol
Measured value
Fat Mass
Testing environment
Lab conditions and equipment
Life stage
Early adult
Background Strain
involves: C57BL/6JTyr;C57BL/6N
Phenotyping center
WTSI

* The high throughput nature of the IMPC means that large control sample sizes may accumulate over a long period of time. See the animal welfare guidelines for more information.

Fat Mass / Box plot
Fat Mass / Scatter plot

Results of statistical analysis

Summary statistics of all data in the dataset

Statistical method

Batch effect significant true
Variance significant true
Genotype*Sex interaction effect p value 6.25x10-2
Genotype parameter estimate -1.722
Genotype standard error estimate 0.589
Genotype Effect P Value 6.25x10-2
Sex Parameter Estimate -1.722
Sex Standard Error Estimate 0.144
Sex Effect P Value 6.25x10-2
Intercept Estimate -8.530
Intercept Estimate Standard Error 0.489
Sex Male KO P Value 6.25x10-2
Sex Female KO P Value 6.25x10-2
WT Residuals Normality Tests 1.64x10-3
KO Residuals Normality Tests 3.81x10-1

Windowing parameters

View documentation about soft windowing
Sharpness (k) 8.324
Bandwidth (l)57

Experimental data download

Download data as:  

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