A Dexa-scan analysis phenotypic assay was performed on 1610 mice. The charts show the results of measuring Lean Mass in 8 female, 8 male mutants compared to 778 female, 816 male controls. The mutants are for the Ldhatm1a(EUCOMM)Wtsi allele.
increased lean body mass
Loading data
P-values equal or lower to 10-4 (P < 0.0001) are marked as significant.
Lean Mass | WTSI | Ldhatm1a(EUCOMM)Wtsi | heterozygote | Early adult | EPD0070_2_G04 | 3.93x10-8 | 9.06x10-2 | 9.06x10-2 |
Ldha data charts
Lean MassExperiments performed
Associated phenotype
Zygosity
heterozygote
Testing protocol
Measured value
Lean Mass
Testing environment
Lab conditions and equipment
Life stage
Early adult
Background Strain
involves: C57BL/6JTyr;C57BL/6N
Phenotyping center
WTSI
* The high throughput nature of the IMPC means that large control sample sizes may accumulate over a long period of time. See the animal welfare guidelines for more information.
Lean Mass / Box plot
Lean Mass / Scatter plot
Results of statistical analysis
Genotype P value
9.06x10-2
Genotype*Female P value
9.06x10-2
Genotype*Male P value
3.93x10-8
Classification
Overally insignificant [level = 1e-04 , pvalue = 0.0905780148059598 ]; but with phenotype threshold value 1e-04 - males only
Summary statistics of all data in the dataset
Statistical method
Batch effect significant | true |
Variance significant | true |
Genotype*Sex interaction effect p value | 9.06x10-2 |
Genotype parameter estimate | 2.055 |
Genotype standard error estimate | 0.531 |
Genotype Effect P Value | 9.06x10-2 |
Sex Parameter Estimate | 2.055 |
Sex Standard Error Estimate | 0.196 |
Sex Effect P Value | 9.06x10-2 |
Intercept Estimate | 7.298 |
Intercept Estimate Standard Error | 0.652 |
Sex Male KO P Value | 9.06x10-2 |
Sex Female KO P Value | 9.06x10-2 |
WT Residuals Normality Tests | 2.4x10-4 |
KO Residuals Normality Tests | 1.93x10-1 |
Statistical analysis API access
Experimental data download
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