A Dexa-scan analysis phenotypic assay was performed on 1610 mice. The charts show the results of measuring Bone Mineral Density (excluding skull) in 8 female, 8 male mutants compared to 778 female, 816 male controls. The mutants are for the Ldhatm1a(EUCOMM)Wtsi allele.
increased bone mineral density
Loading data
P-values equal or lower to 10-4 (P < 0.0001) are marked as significant.
Bone Mineral Density (excluding skull) | WTSI | Ldhatm1a(EUCOMM)Wtsi | heterozygote | Early adult | EPD0070_2_G04 | 4.34x10-5 | 8.08x10-1 | 8.08x10-1 |
Ldha data charts
Bone Mineral Density (excluding skull)Experiments performed
Associated phenotype
Zygosity
heterozygote
Testing protocol
Measured value
Bone Mineral Density (excluding skull)
Testing environment
Lab conditions and equipment
Life stage
Early adult
Background Strain
involves: C57BL/6JTyr;C57BL/6N
Phenotyping center
WTSI
* The high throughput nature of the IMPC means that large control sample sizes may accumulate over a long period of time. See the animal welfare guidelines for more information.
Bone Mineral Density (excluding skull) / Box plot
Bone Mineral Density (excluding skull) / Scatter plot
Results of statistical analysis
Genotype P value
8.08x10-1
Genotype*Female P value
8.08x10-1
Genotype*Male P value
4.34x10-5
Classification
With phenotype threshold value 1e-04 - Significant for males only
Summary statistics of all data in the dataset
Statistical method
Batch effect significant | true |
Variance significant | true |
Genotype*Sex interaction effect p value | 8.08x10-1 |
Genotype parameter estimate | -0.000 |
Genotype standard error estimate | 0.001 |
Genotype Effect P Value | 8.08x10-1 |
Sex Parameter Estimate | -0.000 |
Sex Standard Error Estimate | 0.000 |
Sex Effect P Value | 8.08x10-1 |
Intercept Estimate | 0.041 |
Intercept Estimate Standard Error | 0.001 |
Sex Male KO P Value | 8.08x10-1 |
Sex Female KO P Value | 8.08x10-1 |
WT Residuals Normality Tests | 4.46x10-2 |
KO Residuals Normality Tests | 7.37x10-2 |
Statistical analysis API access
Experimental data download
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