A Clinical Chemistry phenotypic assay was performed on 1303 mice. The charts show the results of measuring Total bilirubin in 5 female, 8 male mutants compared to 643 female, 647 male controls. The mutants are for the Igfbp6em1(IMPC)J allele.
decreased circulating bilirubin level
Loading data
P-values equal or lower to 10-4 (P < 0.0001) are marked as significant.
| Total bilirubin | JAX | Igfbp6em1(IMPC)J | homozygote | Early adult | JR37643 | 9.56x10-5 | 7.15x10-3 | 7.15x10-3 | |
Igfbp6 data charts
Total bilirubinExperiments performed
Associated phenotype
Zygosity
homozygote
Testing protocol
Measured value
Total bilirubin
Testing environment
Lab conditions and equipment
Life stage
Early adult
Background Strain
involves: C57BL/6NJ
Phenotyping center
JAX
* The high throughput nature of the IMPC means that large control sample sizes may accumulate over a long period of time. See the animal welfare guidelines for more information.
Total bilirubin / Box plot
Total bilirubin / Scatter plot
Results of statistical analysis
Genotype P value
7.15x10-3
Genotype*Female P value
7.15x10-3
Genotype*Male P value
9.56x10-5
Classification
Overally insignificant [level = 1e-04 , pvalue = 0.0071470794245081 ]; but with phenotype threshold value 1e-04 - different direction for the sexes
Summary statistics of all data in the dataset
Statistical method
| Batch effect significant | true |
| Variance significant | true |
| Genotype*Sex interaction effect p value | 7.15x10-3 |
| Genotype parameter estimate | 0.000 |
| Genotype standard error estimate | 0.013 |
| Genotype Effect P Value | 7.15x10-3 |
| Sex Parameter Estimate | 0.000 |
| Sex Standard Error Estimate | 0.006 |
| Sex Effect P Value | 7.15x10-3 |
| Intercept Estimate | 0.171 |
| Intercept Estimate Standard Error | 0.015 |
| Sex Male KO P Value | 7.15x10-3 |
| Sex Female KO P Value | 7.15x10-3 |
| WT Residuals Normality Tests | 5.4x10-10 |
| KO Residuals Normality Tests | 6.06x10-2 |
Statistical analysis API access
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