A Clinical Chemistry phenotypic assay was performed on 1303 mice. The charts show the results of measuring Alkaline phosphatase in 5 female, 8 male mutants compared to 643 female, 647 male controls. The mutants are for the Igfbp6em1(IMPC)J allele.
increased circulating alkaline phosphatase level
Loading data
P-values equal or lower to 10-4 (P < 0.0001) are marked as significant.
Alkaline phosphatase | JAX | Igfbp6em1(IMPC)J | homozygote | Early adult | JR37643 | 8.63x10-1 | 1.56x10-7 | 1.56x10-7 |
Igfbp6 data charts
Alkaline phosphataseExperiments performed
Associated phenotype
Zygosity
homozygote
Testing protocol
Measured value
Alkaline phosphatase
Testing environment
Lab conditions and equipment
Life stage
Early adult
Background Strain
involves: C57BL/6NJ
Phenotyping center
JAX
* The high throughput nature of the IMPC means that large control sample sizes may accumulate over a long period of time. See the animal welfare guidelines for more information.
Alkaline phosphatase / Box plot
Alkaline phosphatase / Scatter plot
Results of statistical analysis
Genotype P value
1.56x10-7
Genotype*Female P value
1.56x10-7
Genotype*Male P value
8.63x10-1
Classification
Overally significant [level = 1e-04 , pvalue = 1.5635659544877e-07 ]; and with phenotype threshold value 1e-04 - females only
Summary statistics of all data in the dataset
Statistical method
Batch effect significant | true |
Variance significant | true |
Genotype*Sex interaction effect p value | 1.56x10-7 |
Genotype parameter estimate | -31.036 |
Genotype standard error estimate | 4.355 |
Genotype Effect P Value | 1.56x10-7 |
Sex Parameter Estimate | -31.036 |
Sex Standard Error Estimate | 1.089 |
Sex Effect P Value | 1.56x10-7 |
Intercept Estimate | 127.924 |
Intercept Estimate Standard Error | 3.012 |
Sex Male KO P Value | 1.56x10-7 |
Sex Female KO P Value | 1.56x10-7 |
WT Residuals Normality Tests | 1.25x10-8 |
KO Residuals Normality Tests | 5.1x10-1 |
Statistical analysis API access
Experimental data download
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