increased circulating alkaline phosphatase level

  Loading data
P-values equal or lower to 10-4 (P < 0.0001) are marked as significant.
Alkaline phosphataseJAXIgfbp6em1(IMPC)JhomozygoteEarly adultJR376438.63x10-11.56x10-71.56x10-7

Igfbp6 data charts

Alkaline phosphatase
Combination tested with the lowest p-value of 1.56x10-7
Experiments performed

A Clinical Chemistry phenotypic assay was performed on 1303 mice. The charts show the results of measuring Alkaline phosphatase in 5 female, 8 male mutants compared to 643 female, 647 male controls. The mutants are for the Igfbp6em1(IMPC)J allele.

Associated phenotype
Zygosity
homozygote
Testing protocol
Measured value
Alkaline phosphatase
Testing environment
Lab conditions and equipment
Life stage
Early adult
Background Strain
involves: C57BL/6NJ
Phenotyping center
JAX

* The high throughput nature of the IMPC means that large control sample sizes may accumulate over a long period of time. See the animal welfare guidelines for more information.

Alkaline phosphatase / Box plot
Alkaline phosphatase / Scatter plot

Results of statistical analysis

Summary statistics of all data in the dataset

Statistical method

Batch effect significant true
Variance significant true
Genotype*Sex interaction effect p value 1.56x10-7
Genotype parameter estimate -31.036
Genotype standard error estimate 4.355
Genotype Effect P Value 1.56x10-7
Sex Parameter Estimate -31.036
Sex Standard Error Estimate 1.089
Sex Effect P Value 1.56x10-7
Intercept Estimate 127.924
Intercept Estimate Standard Error 3.012
Sex Male KO P Value 1.56x10-7
Sex Female KO P Value 1.56x10-7
WT Residuals Normality Tests 1.25x10-8
KO Residuals Normality Tests 5.1x10-1

Windowing parameters

View documentation about soft windowing
Sharpness (k) 3.327
Bandwidth (l)856

Experimental data download

Download data as:  

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