A Echo phenotypic assay was performed on 1634 mice. The charts show the results of measuring LVAWd in 8 female, 8 male mutants compared to 832 female, 786 male controls. The mutants are for the Ergem1(IMPC)Bay allele.
increased heart left ventricle size
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P-values equal or lower to 10-4 (P < 0.0001) are marked as significant.
LVAWd | BCM | Ergem1(IMPC)Bay | heterozygote | Early adult | ERGCB | 4.18x10-9 | 4.3x10-1 | 4.3x10-1 |
Erg data charts
LVAWdExperiments performed
Associated phenotype
Zygosity
heterozygote
Testing protocol
Measured value
LVAWd
Testing environment
Lab conditions and equipment
Life stage
Early adult
Background Strain
involves: C57BL/6N
Phenotyping center
BCM
* The high throughput nature of the IMPC means that large control sample sizes may accumulate over a long period of time. See the animal welfare guidelines for more information.
LVAWd / Box plot
LVAWd / Scatter plot
Results of statistical analysis
Genotype P value
4.3x10-1
Genotype*Female P value
4.3x10-1
Genotype*Male P value
4.18x10-9
Classification
Overally insignificant [level = 1e-04 , pvalue = 0.429572153399859 ]; but with phenotype threshold value 1e-04 - males only
Summary statistics of all data in the dataset
Statistical method
Batch effect significant | true |
Variance significant | true |
Genotype*Sex interaction effect p value | 4.3x10-1 |
Genotype parameter estimate | 0.039 |
Genotype standard error estimate | 0.047 |
Genotype Effect P Value | 4.3x10-1 |
Sex Parameter Estimate | 0.039 |
Sex Standard Error Estimate | 0.006 |
Sex Effect P Value | 4.3x10-1 |
Intercept Estimate | 0.869 |
Intercept Estimate Standard Error | 0.005 |
Sex Male KO P Value | 4.3x10-1 |
Sex Female KO P Value | 4.3x10-1 |
WT Residuals Normality Tests | 3.48x10-12 |
KO Residuals Normality Tests | 3.42x10-2 |
Statistical analysis API access
Experimental data download
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