decreased leukocyte cell number

Loading data

P-values equal or lower to 10^-4 (P < 0.0001) are marked as significant.



White blood cell count	BCM	Erg^em1(IMPC)Bay	heterozygote		Early adult	ERGCB				2.3x10^-7	2.07x10^-4	2.07x10^-4

Erg data charts

White blood cell count

Combination tested with the lowest p-value of 2.3x10^-7

Experiments performed

A Hematology phenotypic assay was performed on 181 mice. The charts show the results of measuring White blood cell count in 6 female, 7 male mutants compared to 83 female, 85 male controls. The mutants are for the Erg^em1(IMPC)Bay allele.

Associated phenotype

decreased leukocyte cell number

Zygosity

heterozygote

Testing protocol

Hematology

Measured value

White blood cell count

Testing environment

Lab conditions and equipment

Life stage

Early adult

Background Strain

involves: C57BL/6N

Phenotyping center

BCM

* The high throughput nature of the IMPC means that large control sample sizes may accumulate over a long period of time. See the animal welfare guidelines for more information.

White blood cell count / Box plot

White blood cell count / Scatter plot

Results of statistical analysis

Genotype P value

2.07x10^-4

Genotype*Female P value

2.07x10^-4

Genotype*Male P value

2.3x10^-7

Classification

Overally insignificant [level = 1e-04 , pvalue = 0.000206667446033076 ]; but with phenotype threshold value 1e-04 - different size as males greater

Summary statistics of all data in the dataset

Statistical method



Batch effect significant	false
Variance significant	true
Genotype*Sex interaction effect p value	2.07x10^-4
Genotype parameter estimate	0.991
Genotype standard error estimate	0.316
Genotype Effect P Value	2.07x10^-4
Sex Parameter Estimate	0.991
Sex Standard Error Estimate	0.382
Sex Effect P Value	2.07x10^-4
Intercept Estimate	3.069
Intercept Estimate Standard Error	1.388
Sex Male KO P Value	2.07x10^-4
Sex Female KO P Value	2.07x10^-4
WT Residuals Normality Tests	1.19x10^-2
KO Residuals Normality Tests	1.17x10^-1