decreased total retina thickness

  Loading data
P-values equal or lower to 10-4 (P < 0.0001) are marked as significant.
Left total retinal thicknessICSPlscr1tm1b(EUCOMM)HmguhomozygoteEarly adultIP00004675a1.13x10-18.16x10-148.41x10-14
Right total retinal thicknessICSPlscr1tm1b(EUCOMM)HmguhomozygoteEarly adultIP00004675a1.93x10-17.69x10-107.03x10-10

Plscr1 data charts

Left total retinal thickness
Combination tested with the lowest p-value of 8.16x10-14
Experiments performed

A Eye Morphology phenotypic assay was performed on 802 mice. The charts show the results of measuring Left total retinal thickness in 6 female, 5 male mutants compared to 382 female, 409 male controls. The mutants are for the Plscr1tm1b(EUCOMM)Hmgu allele.

Associated phenotype
Zygosity
homozygote
Testing protocol
Measured value
Left total retinal thickness
Testing environment
Lab conditions and equipment
Life stage
Early adult
Background Strain
involves: C57BL/6N
Phenotyping center
ICS

* The high throughput nature of the IMPC means that large control sample sizes may accumulate over a long period of time. See the animal welfare guidelines for more information.

Left total retinal thickness / Box plot
Left total retinal thickness / Scatter plot

Results of statistical analysis

Summary statistics of all data in the dataset

Statistical method

Batch effect significant false
Variance significant true
Genotype*Sex interaction effect p value 8.41x10-14
Genotype parameter estimate -1.004
Genotype standard error estimate 2.878
Genotype Effect P Value 8.41x10-14
Sex Parameter Estimate -1.004
Sex Standard Error Estimate 0.651
Sex Effect P Value 8.41x10-14
Intercept Estimate 224.471
Intercept Estimate Standard Error 0.463
Sex Male KO P Value 8.41x10-14
Sex Female KO P Value 8.41x10-14
WT Residuals Normality Tests 4.92x10-2
KO Residuals Normality Tests 1.39x10-4

Windowing parameters

View documentation about soft windowing
Sharpness (k) 0.815
Bandwidth (l)734

Experimental data download

Download data as:  

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