A Eye Morphology phenotypic assay was performed on 802 mice. The charts show the results of measuring Left total retinal thickness in 6 female, 5 male mutants compared to 382 female, 409 male controls. The mutants are for the Plscr1tm1b(EUCOMM)Hmgu allele.
decreased total retina thickness
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P-values equal or lower to 10-4 (P < 0.0001) are marked as significant.
Left total retinal thickness | ICS | Plscr1tm1b(EUCOMM)Hmgu | homozygote | Early adult | IP00004675a | 1.13x10-1 | 8.16x10-14 | 8.41x10-14 | |
Right total retinal thickness | ICS | Plscr1tm1b(EUCOMM)Hmgu | homozygote | Early adult | IP00004675a | 1.93x10-1 | 7.69x10-10 | 7.03x10-10 |
Plscr1 data charts
Left total retinal thicknessExperiments performed
Associated phenotype
Zygosity
homozygote
Testing protocol
Measured value
Left total retinal thickness
Testing environment
Lab conditions and equipment
Life stage
Early adult
Background Strain
involves: C57BL/6N
Phenotyping center
ICS
* The high throughput nature of the IMPC means that large control sample sizes may accumulate over a long period of time. See the animal welfare guidelines for more information.
Left total retinal thickness / Box plot
Left total retinal thickness / Scatter plot
Results of statistical analysis
Genotype P value
8.41x10-14
Genotype*Female P value
8.16x10-14
Genotype*Male P value
1.13x10-1
Classification
Overally significant [level = 1e-04 , pvalue = 8.41167571185367e-14 ]; and with phenotype threshold value 1e-04 - females only
Summary statistics of all data in the dataset
Statistical method
Batch effect significant | false |
Variance significant | true |
Genotype*Sex interaction effect p value | 8.41x10-14 |
Genotype parameter estimate | -1.004 |
Genotype standard error estimate | 2.878 |
Genotype Effect P Value | 8.41x10-14 |
Sex Parameter Estimate | -1.004 |
Sex Standard Error Estimate | 0.651 |
Sex Effect P Value | 8.41x10-14 |
Intercept Estimate | 224.471 |
Intercept Estimate Standard Error | 0.463 |
Sex Male KO P Value | 8.41x10-14 |
Sex Female KO P Value | 8.41x10-14 |
WT Residuals Normality Tests | 4.92x10-2 |
KO Residuals Normality Tests | 1.39x10-4 |
Statistical analysis API access
Experimental data download
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