A Electrocardiogram (ECG) phenotypic assay was performed on 445 mice. The charts show the results of measuring QRS in 7 female, 7 male mutants compared to 217 female, 214 male controls. The mutants are for the Plscr1tm1b(EUCOMM)Hmgu allele.
shortened QRS complex duration
Loading data
P-values equal or lower to 10-4 (P < 0.0001) are marked as significant.
QRS | ICS | Plscr1tm1b(EUCOMM)Hmgu | homozygote | Early adult | IP00004675a | 1.92x10-1 | 4.37x10-5 | 4.37x10-5 |
Plscr1 data charts
QRSExperiments performed
Associated phenotype
Zygosity
homozygote
Testing protocol
Measured value
QRS
Testing environment
Lab conditions and equipment
Life stage
Early adult
Background Strain
involves: C57BL/6N
Phenotyping center
ICS
* The high throughput nature of the IMPC means that large control sample sizes may accumulate over a long period of time. See the animal welfare guidelines for more information.
QRS / Box plot
QRS / Scatter plot
Results of statistical analysis
Genotype P value
4.37x10-5
Genotype*Female P value
4.37x10-5
Genotype*Male P value
1.92x10-1
Classification
Overally significant [level = 1e-04 , pvalue = 4.37271182522903e-05 ]; and with phenotype threshold value 1e-04 - females only
Summary statistics of all data in the dataset
Statistical method
Batch effect significant | true |
Variance significant | true |
Genotype*Sex interaction effect p value | 4.37x10-5 |
Genotype parameter estimate | -0.340 |
Genotype standard error estimate | 0.576 |
Genotype Effect P Value | 4.37x10-5 |
Sex Parameter Estimate | -0.340 |
Sex Standard Error Estimate | 0.193 |
Sex Effect P Value | 4.37x10-5 |
Intercept Estimate | 13.122 |
Intercept Estimate Standard Error | 0.285 |
Sex Male KO P Value | 4.37x10-5 |
Sex Female KO P Value | 4.37x10-5 |
WT Residuals Normality Tests | 1.59x10-1 |
KO Residuals Normality Tests | 1.64x10-1 |
Statistical analysis API access
Experimental data download
Download data as: