abnormal heart left ventricle morphology

  Loading data
P-values equal or lower to 10-4 (P < 0.0001) are marked as significant.
LVIDdBCMAldobtm2b(EUCOMM)WtsihomozygoteEarly adultALDEB2.2x10-63.76x10-41.62x10-7
End-Diastolic DiameterBCMAldobtm2b(EUCOMM)WtsihomozygoteEarly adultALDEB9.58x10-63.1x10-44.28x10-7
LVIDsBCMAldobtm2b(EUCOMM)WtsihomozygoteEarly adultALDEB4.32x10-51.3x10-34.34x10-6
End-Systolic DiameterBCMAldobtm2b(EUCOMM)WtsihomozygoteEarly adultALDEB1x10-42.62x10-31.34x10-5

Aldob data charts

LVIDd
Combination tested with the lowest p-value of 1.62x10-7
Experiments performed

A Echo phenotypic assay was performed on 1632 mice. The charts show the results of measuring LVIDd in 8 female, 6 male mutants compared to 832 female, 786 male controls. The mutants are for the Aldobtm2b(EUCOMM)Wtsi allele.

Associated phenotype
Zygosity
homozygote
Testing protocol
Measured value
LVIDd
Testing environment
Lab conditions and equipment
Life stage
Early adult
Background Strain
involves: C57BL/6N
Phenotyping center
BCM

* The high throughput nature of the IMPC means that large control sample sizes may accumulate over a long period of time. See the animal welfare guidelines for more information.

LVIDd / Box plot
LVIDd / Scatter plot

Results of statistical analysis

Summary statistics of all data in the dataset

Statistical method

Batch effect significant true
Variance significant true
Genotype*Sex interaction effect p value 1.62x10-7
Genotype parameter estimate 0.156
Genotype standard error estimate 0.085
Genotype Effect P Value 1.62x10-7
Sex Parameter Estimate 0.156
Sex Standard Error Estimate 0.023
Sex Effect P Value 1.62x10-7
Intercept Estimate 3.972
Intercept Estimate Standard Error 0.019
Sex Male KO P Value 1.62x10-7
Sex Female KO P Value 1.62x10-7
WT Residuals Normality Tests 8.45x10-2
KO Residuals Normality Tests 1.28x10-1

Windowing parameters

View documentation about soft windowing
Sharpness (k) 2.770
Bandwidth (l)420

Experimental data download

Download data as:  

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