A Echo phenotypic assay was performed on 1632 mice. The charts show the results of measuring LVIDd in 8 female, 6 male mutants compared to 832 female, 786 male controls. The mutants are for the Aldobtm2b(EUCOMM)Wtsi allele.
abnormal heart left ventricle morphology
Loading data
P-values equal or lower to 10-4 (P < 0.0001) are marked as significant.
LVIDd | BCM | Aldobtm2b(EUCOMM)Wtsi | homozygote | Early adult | ALDEB | 2.2x10-6 | 3.76x10-4 | 1.62x10-7 | |
End-Diastolic Diameter | BCM | Aldobtm2b(EUCOMM)Wtsi | homozygote | Early adult | ALDEB | 9.58x10-6 | 3.1x10-4 | 4.28x10-7 | |
LVIDs | BCM | Aldobtm2b(EUCOMM)Wtsi | homozygote | Early adult | ALDEB | 4.32x10-5 | 1.3x10-3 | 4.34x10-6 | |
End-Systolic Diameter | BCM | Aldobtm2b(EUCOMM)Wtsi | homozygote | Early adult | ALDEB | 1x10-4 | 2.62x10-3 | 1.34x10-5 |
Aldob data charts
LVIDdExperiments performed
Associated phenotype
Zygosity
homozygote
Testing protocol
Measured value
LVIDd
Testing environment
Lab conditions and equipment
Life stage
Early adult
Background Strain
involves: C57BL/6N
Phenotyping center
BCM
* The high throughput nature of the IMPC means that large control sample sizes may accumulate over a long period of time. See the animal welfare guidelines for more information.
LVIDd / Box plot
LVIDd / Scatter plot
Results of statistical analysis
Genotype P value
1.62x10-7
Genotype*Female P value
3.76x10-4
Genotype*Male P value
2.2x10-6
Classification
With phenotype threshold value 1e-04 - both sexes equally
Summary statistics of all data in the dataset
Statistical method
Batch effect significant | true |
Variance significant | true |
Genotype*Sex interaction effect p value | 1.62x10-7 |
Genotype parameter estimate | 0.156 |
Genotype standard error estimate | 0.085 |
Genotype Effect P Value | 1.62x10-7 |
Sex Parameter Estimate | 0.156 |
Sex Standard Error Estimate | 0.023 |
Sex Effect P Value | 1.62x10-7 |
Intercept Estimate | 3.972 |
Intercept Estimate Standard Error | 0.019 |
Sex Male KO P Value | 1.62x10-7 |
Sex Female KO P Value | 1.62x10-7 |
WT Residuals Normality Tests | 8.45x10-2 |
KO Residuals Normality Tests | 1.28x10-1 |
Statistical analysis API access
Experimental data download
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