decreased bone mineral density

  Loading data
P-values equal or lower to 10-4 (P < 0.0001) are marked as significant.
Bone Mineral Density (excluding skull)BCMAldobtm2b(EUCOMM)WtsihomozygoteEarly adultALDEB3.95x10-42.82x10-71.28x10-8

Aldob data charts

Bone Mineral Density (excluding skull)
Combination tested with the lowest p-value of 1.28x10-8
Experiments performed

A Body Composition (DEXA lean/fat) phenotypic assay was performed on 807 mice. The charts show the results of measuring Bone Mineral Density (excluding skull) in 8 female, 7 male mutants compared to 403 female, 389 male controls. The mutants are for the Aldobtm2b(EUCOMM)Wtsi allele.

Associated phenotype
Zygosity
homozygote
Testing protocol
Measured value
Bone Mineral Density (excluding skull)
Testing environment
Lab conditions and equipment
Life stage
Early adult
Background Strain
involves: C57BL/6N
Phenotyping center
BCM

* The high throughput nature of the IMPC means that large control sample sizes may accumulate over a long period of time. See the animal welfare guidelines for more information.

Bone Mineral Density (excluding skull) / Box plot
Bone Mineral Density (excluding skull) / Scatter plot

Results of statistical analysis

Summary statistics of all data in the dataset

Statistical method

Batch effect significant true
Variance significant true
Genotype*Sex interaction effect p value 1.28x10-8
Genotype parameter estimate -0.004
Genotype standard error estimate 0.000
Genotype Effect P Value 1.28x10-8
Sex Parameter Estimate -0.004
Sex Standard Error Estimate 0.000
Sex Effect P Value 1.28x10-8
Intercept Estimate 0.037
Intercept Estimate Standard Error 0.001
Sex Male KO P Value 1.28x10-8
Sex Female KO P Value 1.28x10-8
WT Residuals Normality Tests 3.3x10-2
KO Residuals Normality Tests 7.06x10-1

Windowing parameters

View documentation about soft windowing
Sharpness (k) 2.305
Bandwidth (l)495

Experimental data download

Download data as:  

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