increased vertical activity

Loading data

P-values equal or lower to 10^-4 (P < 0.0001) are marked as significant.



Number of rears - total	TCP	Arhgef33^em1(IMPC)Tcp	homozygote		Early adult	TCPR1466_AEJW				4.55x10^-5	3.95x10^-2	4.51x10^-2

Arhgef33 data charts

Number of rears - total

Combination tested with the lowest p-value of 4.55x10^-5

Experiments performed

A Open Field phenotypic assay was performed on 1083 mice. The charts show the results of measuring Number of rears - total in 8 female, 7 male mutants compared to 555 female, 513 male controls. The mutants are for the Arhgef33^em1(IMPC)Tcp allele.

Associated phenotype

increased vertical activity

Zygosity

homozygote

Testing protocol

Open Field

Measured value

Number of rears - total

Testing environment

Lab conditions and equipment

Life stage

Early adult

Background Strain

involves: C57BL/6NCrl

Phenotyping center

TCP

* The high throughput nature of the IMPC means that large control sample sizes may accumulate over a long period of time. See the animal welfare guidelines for more information.

Number of rears - total / Box plot

Number of rears - total / Scatter plot

Results of statistical analysis

Genotype P value

4.51x10^-2

Genotype*Female P value

3.95x10^-2

Genotype*Male P value

4.55x10^-5

Classification

Overally insignificant [level = 1e-04 , pvalue = 0.045064628313376 ]; but with phenotype threshold value 1e-04 - different size as males greater

Summary statistics of all data in the dataset

Statistical method



Batch effect significant	true
Variance significant	true
Genotype*Sex interaction effect p value	4.51x10^-2
Genotype parameter estimate	51.853
Genotype standard error estimate	33.324
Genotype Effect P Value	4.51x10^-2
Sex Parameter Estimate	51.853
Sex Standard Error Estimate	5.983
Sex Effect P Value	4.51x10^-2
Intercept Estimate	163.402
Intercept Estimate Standard Error	5.064
Sex Male KO P Value	4.51x10^-2
Sex Female KO P Value	4.51x10^-2
WT Residuals Normality Tests	1.64x10^-11
KO Residuals Normality Tests	2.45x10^-1