A Grip Strength phenotypic assay was performed on 3141 mice. The charts show the results of measuring Forelimb grip strength measurement mean in 7 female, 7 male mutants compared to 1567 female, 1560 male controls. The mutants are for the Gpr152tm1b(EUCOMM)Wtsi allele.
decreased grip strength
Loading data
P-values equal or lower to 10-4 (P < 0.0001) are marked as significant.
Forelimb grip strength measurement mean | WTSI | Gpr152tm1b(EUCOMM)Wtsi | homozygote | Early adult | MUBW | 3.2x10-7 | 7.47x10-5 | 4.39x10-8 | |
Forelimb grip strength normalised against body weight | WTSI | Gpr152tm1b(EUCOMM)Wtsi | homozygote | Early adult | MUBW | 7.22x10-6 | 9.74x10-6 | 5.71x10-8 |
Gpr152 data charts
Forelimb grip strength measurement meanExperiments performed
Associated phenotype
Zygosity
homozygote
Testing protocol
Measured value
Forelimb grip strength measurement mean
Testing environment
Lab conditions and equipment
Life stage
Early adult
Background Strain
involves: C57BL/6N
Phenotyping center
WTSI
* The high throughput nature of the IMPC means that large control sample sizes may accumulate over a long period of time. See the animal welfare guidelines for more information.
Forelimb grip strength measurement mean / Box plot
Forelimb grip strength measurement mean / Scatter plot
Results of statistical analysis
Genotype P value
4.39x10-8
Genotype*Female P value
7.47x10-5
Genotype*Male P value
3.2x10-7
Classification
With phenotype threshold value 1e-04 - both sexes equally
Summary statistics of all data in the dataset
Statistical method
Batch effect significant | true |
Variance significant | true |
Genotype*Sex interaction effect p value | 4.39x10-8 |
Genotype parameter estimate | 5.070 |
Genotype standard error estimate | 5.038 |
Genotype Effect P Value | 4.39x10-8 |
Sex Parameter Estimate | 5.070 |
Sex Standard Error Estimate | 2.364 |
Sex Effect P Value | 4.39x10-8 |
Intercept Estimate | 50.061 |
Intercept Estimate Standard Error | 8.086 |
Sex Male KO P Value | 4.39x10-8 |
Sex Female KO P Value | 4.39x10-8 |
WT Residuals Normality Tests | 3.52x10-1 |
KO Residuals Normality Tests | 2.95x10-1 |
Statistical analysis API access
Experimental data download
Download data as: