decreased grip strength

  Loading data
P-values equal or lower to 10-4 (P < 0.0001) are marked as significant.
Forelimb grip strength measurement meanWTSIGpr152tm1b(EUCOMM)WtsihomozygoteEarly adultMUBW3.2x10-77.47x10-54.39x10-8
Forelimb grip strength normalised against body weightWTSIGpr152tm1b(EUCOMM)WtsihomozygoteEarly adultMUBW7.22x10-69.74x10-65.71x10-8

Gpr152 data charts

Forelimb grip strength measurement mean
Combination tested with the lowest p-value of 4.39x10-8
Experiments performed

A Grip Strength phenotypic assay was performed on 3141 mice. The charts show the results of measuring Forelimb grip strength measurement mean in 7 female, 7 male mutants compared to 1567 female, 1560 male controls. The mutants are for the Gpr152tm1b(EUCOMM)Wtsi allele.

Associated phenotype
Zygosity
homozygote
Testing protocol
Measured value
Forelimb grip strength measurement mean
Testing environment
Lab conditions and equipment
Life stage
Early adult
Background Strain
involves: C57BL/6N
Phenotyping center
WTSI

* The high throughput nature of the IMPC means that large control sample sizes may accumulate over a long period of time. See the animal welfare guidelines for more information.

Forelimb grip strength measurement mean / Box plot
Forelimb grip strength measurement mean / Scatter plot

Results of statistical analysis

Summary statistics of all data in the dataset

Statistical method

Batch effect significant true
Variance significant true
Genotype*Sex interaction effect p value 4.39x10-8
Genotype parameter estimate 5.070
Genotype standard error estimate 5.038
Genotype Effect P Value 4.39x10-8
Sex Parameter Estimate 5.070
Sex Standard Error Estimate 2.364
Sex Effect P Value 4.39x10-8
Intercept Estimate 50.061
Intercept Estimate Standard Error 8.086
Sex Male KO P Value 4.39x10-8
Sex Female KO P Value 4.39x10-8
WT Residuals Normality Tests 3.52x10-1
KO Residuals Normality Tests 2.95x10-1

Windowing parameters

View documentation about soft windowing
Sharpness (k) 1.503
Bandwidth (l)34

Experimental data download

Download data as:  

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