A Immunophenotyping phenotypic assay was performed on 519 mice. The charts show the results of measuring CD4 CD44+CD62L+ NKT cells in 8 female, 8 male mutants compared to 251 female, 252 male controls. The mutants are for the Tmem150bem1(IMPC)Ccpcz allele.
decreased memory-marker CD4-positive NK T cell number
Loading data
P-values equal or lower to 10-4 (P < 0.0001) are marked as significant.
CD4 CD44+CD62L+ NKT cells | CCP-IMG | Tmem150bem1(IMPC)Ccpcz | homozygote | Early adult | CCP-EXDEL-EM1-B6N-Tmem150b | 3.18x10-1 | 2.45x10-12 | 1.79x10-12 |
Tmem150b data charts
CD4 CD44+CD62L+ NKT cellsExperiments performed
Associated phenotype
Zygosity
homozygote
Testing protocol
Measured value
CD4 CD44+CD62L+ NKT cells
Testing environment
Lab conditions and equipment
Life stage
Early adult
Background Strain
involves: C57BL/6NCrl
Phenotyping center
CCP-IMG
* The high throughput nature of the IMPC means that large control sample sizes may accumulate over a long period of time. See the animal welfare guidelines for more information.
CD4 CD44+CD62L+ NKT cells / Box plot
CD4 CD44+CD62L+ NKT cells / Scatter plot
Results of statistical analysis
Genotype P value
1.79x10-12
Genotype*Female P value
2.45x10-12
Genotype*Male P value
3.18x10-1
Classification
Overally significant [level = 1e-04 , pvalue = 1.78967951569575e-12 ]; and with phenotype threshold value 1e-04 - females only
Summary statistics of all data in the dataset
Statistical method
Batch effect significant | true |
Variance significant | true |
Genotype*Sex interaction effect p value | 1.79x10-12 |
Genotype parameter estimate | 1.521 |
Genotype standard error estimate | 19.475 |
Genotype Effect P Value | 1.79x10-12 |
Sex Parameter Estimate | 1.521 |
Sex Standard Error Estimate | 6.467 |
Sex Effect P Value | 1.79x10-12 |
Intercept Estimate | 32.438 |
Intercept Estimate Standard Error | 6.227 |
Sex Male KO P Value | 1.79x10-12 |
Sex Female KO P Value | 1.79x10-12 |
WT Residuals Normality Tests | 3.33x10-35 |
KO Residuals Normality Tests | 4.73x10-3 |
Statistical analysis API access
Experimental data download
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