A Acoustic Startle and Pre-pulse Inhibition (PPI) phenotypic assay was performed on 2821 mice. The charts show the results of measuring % Pre-pulse inhibition - PPI1 in 8 female, 9 male mutants compared to 1399 female, 1405 male controls. The mutants are for the Mogat2em1(IMPC)Mbp allele.
decreased prepulse inhibition
Loading data
P-values equal or lower to 10-4 (P < 0.0001) are marked as significant.
% Pre-pulse inhibition - PPI1 | UC Davis | Mogat2em1(IMPC)Mbp | homozygote | Early adult | CR10349 | 1.73x10-1 | 8.42x10-6 | 1.05x10-5 | |
% Pre-pulse inhibition - Global | UC Davis | Mogat2em1(IMPC)Mbp | homozygote | Early adult | CR10349 | 4.45x10-2 | 3.06x10-5 | 2.56x10-5 | |
% Pre-pulse inhibition - PPI2 | UC Davis | Mogat2em1(IMPC)Mbp | homozygote | Early adult | CR10349 | 6.75x10-2 | 4.13x10-5 | 3.33x10-5 |
Mogat2 data charts
% Pre-pulse inhibition - PPI1Experiments performed
Associated phenotype
Zygosity
homozygote
Testing protocol
Measured value
% Pre-pulse inhibition - PPI1
Testing environment
Lab conditions and equipment
Life stage
Early adult
Background Strain
involves: C57BL/6NCrl
Phenotyping center
UC Davis
* The high throughput nature of the IMPC means that large control sample sizes may accumulate over a long period of time. See the animal welfare guidelines for more information.
Statistical information
Batch effect significant | false |
Variance significant | true |
Genotype*Sex interaction effect p value | 1.05x10-5 |
Genotype parameter estimate | -0.750 |
Genotype standard error estimate | 6.246 |
Genotype Effect P Value | 1.05x10-5 |
Sex Parameter Estimate | -0.750 |
Sex Standard Error Estimate | 1.241 |
Sex Effect P Value | 1.05x10-5 |
Intercept Estimate | 41.327 |
Intercept Estimate Standard Error | 0.876 |
Sex Male KO P Value | 1.05x10-5 |
Sex Female KO P Value | 1.05x10-5 |
WT Residuals Normality Tests | 2x10-2 |
KO Residuals Normality Tests | 5.84x10-2 |