decreased prepulse inhibition

  Loading data
P-values equal or lower to 10-4 (P < 0.0001) are marked as significant.
% Pre-pulse inhibition - PPI1UC DavisMogat2em1(IMPC)MbphomozygoteEarly adultCR103491.73x10-18.42x10-61.05x10-5
% Pre-pulse inhibition - GlobalUC DavisMogat2em1(IMPC)MbphomozygoteEarly adultCR103494.45x10-23.06x10-52.56x10-5
% Pre-pulse inhibition - PPI2UC DavisMogat2em1(IMPC)MbphomozygoteEarly adultCR103496.75x10-24.13x10-53.33x10-5

Mogat2 data charts

% Pre-pulse inhibition - PPI1
Combination tested with the lowest p-value of 8.42x10-6
Experiments performed

A Acoustic Startle and Pre-pulse Inhibition (PPI) phenotypic assay was performed on 2821 mice. The charts show the results of measuring % Pre-pulse inhibition - PPI1 in 8 female, 9 male mutants compared to 1399 female, 1405 male controls. The mutants are for the Mogat2em1(IMPC)Mbp allele.

Associated phenotype
Zygosity
homozygote
Testing protocol
Measured value
% Pre-pulse inhibition - PPI1
Testing environment
Lab conditions and equipment
Life stage
Early adult
Background Strain
involves: C57BL/6NCrl
Phenotyping center
UC Davis

* The high throughput nature of the IMPC means that large control sample sizes may accumulate over a long period of time. See the animal welfare guidelines for more information.

Statistical information

Batch effect significant false
Variance significant true
Genotype*Sex interaction effect p value 1.05x10-5
Genotype parameter estimate -0.750
Genotype standard error estimate 6.246
Genotype Effect P Value 1.05x10-5
Sex Parameter Estimate -0.750
Sex Standard Error Estimate 1.241
Sex Effect P Value 1.05x10-5
Intercept Estimate 41.327
Intercept Estimate Standard Error 0.876
Sex Male KO P Value 1.05x10-5
Sex Female KO P Value 1.05x10-5
WT Residuals Normality Tests 2x10-2
KO Residuals Normality Tests 5.84x10-2

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