A Clinical Chemistry phenotypic assay was performed on 4117 mice. The charts show the results of measuring Alkaline phosphatase in 7 female, 7 male mutants compared to 2045 female, 2058 male controls. The mutants are for the Galnt18tm1b(KOMP)Wtsi allele.
increased circulating alkaline phosphatase level
Loading data
P-values equal or lower to 10-4 (P < 0.0001) are marked as significant.
Alkaline phosphatase | WTSI | Galnt18tm1b(KOMP)Wtsi | homozygote | Early adult | MUEL | 7.46x10-1 | 3.65x10-7 | 3.65x10-7 |
Galnt18 data charts
Alkaline phosphataseExperiments performed
Associated phenotype
Zygosity
homozygote
Testing protocol
Measured value
Alkaline phosphatase
Testing environment
Lab conditions and equipment
Life stage
Early adult
Background Strain
involves: C57BL/6N
Phenotyping center
WTSI
* The high throughput nature of the IMPC means that large control sample sizes may accumulate over a long period of time. See the animal welfare guidelines for more information.
Alkaline phosphatase / Box plot
Alkaline phosphatase / Scatter plot
Results of statistical analysis
Genotype P value
3.65x10-7
Genotype*Female P value
3.65x10-7
Genotype*Male P value
7.46x10-1
Classification
Overally significant [level = 1e-04 , pvalue = 3.65379881572814e-07 ]; and with phenotype threshold value 1e-04 - females only
Summary statistics of all data in the dataset
Statistical method
Batch effect significant | true |
Variance significant | true |
Genotype*Sex interaction effect p value | 3.65x10-7 |
Genotype parameter estimate | -31.153 |
Genotype standard error estimate | 3.655 |
Genotype Effect P Value | 3.65x10-7 |
Sex Parameter Estimate | -31.153 |
Sex Standard Error Estimate | 0.942 |
Sex Effect P Value | 3.65x10-7 |
Intercept Estimate | 146.977 |
Intercept Estimate Standard Error | 2.939 |
Sex Male KO P Value | 3.65x10-7 |
Sex Female KO P Value | 3.65x10-7 |
WT Residuals Normality Tests | 8.41x10-13 |
KO Residuals Normality Tests | 1.03x10-1 |
Statistical analysis API access
Experimental data download
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