increased bone mineral content

  Loading data
P-values equal or lower to 10-4 (P < 0.0001) are marked as significant.
Bone Mineral Content (excluding skull)MARCKmt2cem2(IMPC)MarcheterozygoteEarly adultKtm2c_cas9_del2-15.58x10-11.9x10-61.9x10-6

Kmt2c data charts

Bone Mineral Content (excluding skull)
Combination tested with the lowest p-value of 1.9x10-6
Experiments performed

A Body Composition (DEXA lean/fat) phenotypic assay was performed on 842 mice. The charts show the results of measuring Bone Mineral Content (excluding skull) in 7 female, 7 male mutants compared to 418 female, 410 male controls. The mutants are for the Kmt2cem2(IMPC)Marc allele.

Associated phenotype
Zygosity
heterozygote
Testing protocol
Measured value
Bone Mineral Content (excluding skull)
Testing environment
Lab conditions and equipment
Life stage
Early adult
Background Strain
involves: C57BL/6N
Phenotyping center
MARC

* The high throughput nature of the IMPC means that large control sample sizes may accumulate over a long period of time. See the animal welfare guidelines for more information.

Bone Mineral Content (excluding skull) / Box plot
Bone Mineral Content (excluding skull) / Scatter plot

Results of statistical analysis

Summary statistics of all data in the dataset

Statistical method

Batch effect significant false
Variance significant true
Genotype*Sex interaction effect p value 1.9x10-6
Genotype parameter estimate -0.071
Genotype standard error estimate 0.010
Genotype Effect P Value 1.9x10-6
Sex Parameter Estimate -0.071
Sex Standard Error Estimate 0.011
Sex Effect P Value 1.9x10-6
Intercept Estimate 0.004
Intercept Estimate Standard Error 0.037
Sex Male KO P Value 1.9x10-6
Sex Female KO P Value 1.9x10-6
WT Residuals Normality Tests 4.55x10-5
KO Residuals Normality Tests 6.71x10-1

Windowing parameters

View documentation about soft windowing
Sharpness (k) 8.324
Bandwidth (l)40

Experimental data download

Download data as:  

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