abnormal bone structure

  Loading data
P-values equal or lower to 10-4 (P < 0.0001) are marked as significant.
Bone AreaMARCKmt2cem2(IMPC)MarcheterozygoteEarly adultKtm2c_cas9_del2-18.89x10-12.11x10-62.11x10-6

Kmt2c data charts

Bone Area
Combination tested with the lowest p-value of 2.11x10-6
Experiments performed

A Body Composition (DEXA lean/fat) phenotypic assay was performed on 842 mice. The charts show the results of measuring Bone Area in 7 female, 7 male mutants compared to 418 female, 410 male controls. The mutants are for the Kmt2cem2(IMPC)Marc allele.

Associated phenotype
Zygosity
heterozygote
Testing protocol
Measured value
Bone Area
Testing environment
Lab conditions and equipment
Life stage
Early adult
Background Strain
involves: C57BL/6N
Phenotyping center
MARC

* The high throughput nature of the IMPC means that large control sample sizes may accumulate over a long period of time. See the animal welfare guidelines for more information.

Bone Area / Box plot
Bone Area / Scatter plot

Results of statistical analysis

Summary statistics of all data in the dataset

Statistical method

Batch effect significant false
Variance significant true
Genotype*Sex interaction effect p value 2.11x10-6
Genotype parameter estimate -0.312
Genotype standard error estimate 0.113
Genotype Effect P Value 2.11x10-6
Sex Parameter Estimate -0.312
Sex Standard Error Estimate 0.120
Sex Effect P Value 2.11x10-6
Intercept Estimate 4.332
Intercept Estimate Standard Error 0.383
Sex Male KO P Value 2.11x10-6
Sex Female KO P Value 2.11x10-6
WT Residuals Normality Tests 6.08x10-1
KO Residuals Normality Tests 2.01x10-1

Windowing parameters

View documentation about soft windowing
Sharpness (k) 1.805
Bandwidth (l)40

Experimental data download

Download data as:  

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