A Body Composition (DEXA lean/fat) phenotypic assay was performed on 842 mice. The charts show the results of measuring Bone Area in 7 female, 7 male mutants compared to 418 female, 410 male controls. The mutants are for the Kmt2cem2(IMPC)Marc allele.
abnormal bone structure
Loading data
P-values equal or lower to 10-4 (P < 0.0001) are marked as significant.
Bone Area | MARC | Kmt2cem2(IMPC)Marc | heterozygote | Early adult | Ktm2c_cas9_del2-1 | 8.89x10-1 | 2.11x10-6 | 2.11x10-6 |
Kmt2c data charts
Bone AreaExperiments performed
Associated phenotype
Zygosity
heterozygote
Testing protocol
Measured value
Bone Area
Testing environment
Lab conditions and equipment
Life stage
Early adult
Background Strain
involves: C57BL/6N
Phenotyping center
MARC
* The high throughput nature of the IMPC means that large control sample sizes may accumulate over a long period of time. See the animal welfare guidelines for more information.
Bone Area / Box plot
Bone Area / Scatter plot
Results of statistical analysis
Genotype P value
2.11x10-6
Genotype*Female P value
2.11x10-6
Genotype*Male P value
8.89x10-1
Classification
Overally significant [level = 1e-04 , pvalue = 2.11162585394121e-06 ]; and with phenotype threshold value 1e-04 - females only
Summary statistics of all data in the dataset
Statistical method
Batch effect significant | false |
Variance significant | true |
Genotype*Sex interaction effect p value | 2.11x10-6 |
Genotype parameter estimate | -0.312 |
Genotype standard error estimate | 0.113 |
Genotype Effect P Value | 2.11x10-6 |
Sex Parameter Estimate | -0.312 |
Sex Standard Error Estimate | 0.120 |
Sex Effect P Value | 2.11x10-6 |
Intercept Estimate | 4.332 |
Intercept Estimate Standard Error | 0.383 |
Sex Male KO P Value | 2.11x10-6 |
Sex Female KO P Value | 2.11x10-6 |
WT Residuals Normality Tests | 6.08x10-1 |
KO Residuals Normality Tests | 2.01x10-1 |
Statistical analysis API access
Experimental data download
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