A Clinical Chemistry phenotypic assay was performed on 520 mice. The charts show the results of measuring Alpha-amylase in 7 female, 7 male mutants compared to 258 female, 248 male controls. The mutants are for the Cadps2em1(IMPC)Rbrc allele.
increased circulating amylase level
Loading data
P-values equal or lower to 10-4 (P < 0.0001) are marked as significant.
| Alpha-amylase | RBRC | Cadps2em1(IMPC)Rbrc | homozygote | Early adult | RIKEN-Cadps2-C02_ | 1.17x10-3 | 2.75x10-3 | 8.54x10-5 | |
Cadps2 data charts
Alpha-amylaseExperiments performed
Associated phenotype
Zygosity
homozygote
Testing protocol
Measured value
Alpha-amylase
Testing environment
Lab conditions and equipment
Life stage
Early adult
Background Strain
involves: C57BL/6NJcl
Phenotyping center
RBRC
* The high throughput nature of the IMPC means that large control sample sizes may accumulate over a long period of time. See the animal welfare guidelines for more information.
Alpha-amylase / Box plot
Alpha-amylase / Scatter plot
Results of statistical analysis
Genotype P value
8.54x10-5
Genotype*Female P value
2.75x10-3
Genotype*Male P value
1.17x10-3
Classification
With phenotype threshold value 1e-04 - both sexes equally
Summary statistics of all data in the dataset
Statistical method
| Batch effect significant | true |
| Variance significant | true |
| Genotype*Sex interaction effect p value | 8.54x10-5 |
| Genotype parameter estimate | 210.529 |
| Genotype standard error estimate | 23.634 |
| Genotype Effect P Value | 8.54x10-5 |
| Sex Parameter Estimate | 210.529 |
| Sex Standard Error Estimate | 14.198 |
| Sex Effect P Value | 8.54x10-5 |
| Intercept Estimate | 729.233 |
| Intercept Estimate Standard Error | 33.132 |
| Sex Male KO P Value | 8.54x10-5 |
| Sex Female KO P Value | 8.54x10-5 |
| WT Residuals Normality Tests | 8.44x10-1 |
| KO Residuals Normality Tests | 5.81x10-1 |
Statistical analysis API access
Experimental data download
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