A Clinical Chemistry phenotypic assay was performed on 262 mice. The charts show the results of measuring Alkaline phosphatase in 8 female, 8 male mutants compared to 128 female, 118 male controls. The mutants are for the Cadps2em1(IMPC)Rbrc allele.
abnormal circulating alkaline phosphatase level
Loading data
P-values equal or lower to 10-4 (P < 0.0001) are marked as significant.
Alkaline phosphatase | RBRC | Cadps2em1(IMPC)Rbrc | homozygote | Late adult | RIKEN-Cadps2-C02_ | 8.43x10-1 | 1.5x10-5 | 4x10-6 |
Cadps2 data charts
Alkaline phosphataseExperiments performed
Associated phenotype
Zygosity
homozygote
Testing protocol
Measured value
Alkaline phosphatase
Testing environment
Lab conditions and equipment
Life stage
Late adult
Background Strain
involves: C57BL/6NJcl
Phenotyping center
RBRC
* The high throughput nature of the IMPC means that large control sample sizes may accumulate over a long period of time. See the animal welfare guidelines for more information.
Alkaline phosphatase / Box plot
Alkaline phosphatase / Scatter plot
Results of statistical analysis
Genotype P value
4x10-6
Genotype*Female P value
1.5x10-5
Genotype*Male P value
8.43x10-1
Classification
Overally significant [level = 1e-04 , pvalue = 4.00409580439261e-06 ]; and with phenotype threshold value 1e-04 - females only
Summary statistics of all data in the dataset
Statistical method
Batch effect significant | false |
Variance significant | true |
Genotype*Sex interaction effect p value | 4x10-6 |
Genotype parameter estimate | -148.570 |
Genotype standard error estimate | 48.201 |
Genotype Effect P Value | 4x10-6 |
Sex Parameter Estimate | -148.570 |
Sex Standard Error Estimate | 27.325 |
Sex Effect P Value | 4x10-6 |
Intercept Estimate | 404.821 |
Intercept Estimate Standard Error | 19.090 |
Sex Male KO P Value | 4x10-6 |
Sex Female KO P Value | 4x10-6 |
WT Residuals Normality Tests | 1.27x10-5 |
KO Residuals Normality Tests | 1.54x10-5 |
Statistical analysis API access
Experimental data download
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