abnormal circulating alkaline phosphatase level

  Loading data
P-values equal or lower to 10-4 (P < 0.0001) are marked as significant.
Alkaline phosphataseRBRCCadps2em1(IMPC)RbrchomozygoteLate adultRIKEN-Cadps2-C02_8.43x10-11.5x10-54x10-6

Cadps2 data charts

Alkaline phosphatase
Combination tested with the lowest p-value of 4x10-6
Experiments performed

A Clinical Chemistry phenotypic assay was performed on 262 mice. The charts show the results of measuring Alkaline phosphatase in 8 female, 8 male mutants compared to 128 female, 118 male controls. The mutants are for the Cadps2em1(IMPC)Rbrc allele.

Associated phenotype
Zygosity
homozygote
Testing protocol
Measured value
Alkaline phosphatase
Testing environment
Lab conditions and equipment
Life stage
Late adult
Background Strain
involves: C57BL/6NJcl
Phenotyping center
RBRC

* The high throughput nature of the IMPC means that large control sample sizes may accumulate over a long period of time. See the animal welfare guidelines for more information.

Alkaline phosphatase / Box plot
Alkaline phosphatase / Scatter plot

Results of statistical analysis

Summary statistics of all data in the dataset

Statistical method

Batch effect significant false
Variance significant true
Genotype*Sex interaction effect p value 4x10-6
Genotype parameter estimate -148.570
Genotype standard error estimate 48.201
Genotype Effect P Value 4x10-6
Sex Parameter Estimate -148.570
Sex Standard Error Estimate 27.325
Sex Effect P Value 4x10-6
Intercept Estimate 404.821
Intercept Estimate Standard Error 19.090
Sex Male KO P Value 4x10-6
Sex Female KO P Value 4x10-6
WT Residuals Normality Tests 1.27x10-5
KO Residuals Normality Tests 1.54x10-5

Windowing parameters

View documentation about soft windowing
Sharpness (k) 8.324
Bandwidth (l)117

Experimental data download

Download data as:  

The IMPC Newsletter

Get highlights of the most important data releases, news and events, delivered straight to your email inbox

Subscribe to newsletter