A Clinical Chemistry phenotypic assay was performed on 1099 mice. The charts show the results of measuring Potassium in 5 female, 5 male mutants compared to 542 female, 547 male controls. The mutants are for the Dusp4tm1a(EUCOMM)Wtsi allele.
decreased circulating potassium level
Loading data
P-values equal or lower to 10-4 (P < 0.0001) are marked as significant.
Potassium | WTSI | Dusp4tm1a(EUCOMM)Wtsi | homozygote | Early adult | EPD0105_5_C02 | 2.61x10-2 | 1.13x10-8 | 1.13x10-8 |
Dusp4 data charts
PotassiumExperiments performed
Associated phenotype
Zygosity
homozygote
Testing protocol
Measured value
Potassium
Testing environment
Lab conditions and equipment
Life stage
Early adult
Background Strain
involves: C57BL/6N
Phenotyping center
WTSI
* The high throughput nature of the IMPC means that large control sample sizes may accumulate over a long period of time. See the animal welfare guidelines for more information.
Potassium / Box plot
Potassium / Scatter plot
Results of statistical analysis
Genotype P value
1.13x10-8
Genotype*Female P value
1.13x10-8
Genotype*Male P value
2.61x10-2
Classification
Overally significant [level = 1e-04 , pvalue = 1.13058525874621e-08 ]; and with phenotype threshold value 1e-04 - different size as females greater
Summary statistics of all data in the dataset
Statistical method
Batch effect significant | true |
Variance significant | true |
Genotype*Sex interaction effect p value | 1.13x10-8 |
Genotype parameter estimate | 0.265 |
Genotype standard error estimate | 0.148 |
Genotype Effect P Value | 1.13x10-8 |
Sex Parameter Estimate | 0.265 |
Sex Standard Error Estimate | 0.044 |
Sex Effect P Value | 1.13x10-8 |
Intercept Estimate | 3.272 |
Intercept Estimate Standard Error | 0.170 |
Sex Male KO P Value | 1.13x10-8 |
Sex Female KO P Value | 1.13x10-8 |
WT Residuals Normality Tests | 2.33x10-5 |
KO Residuals Normality Tests | 1.27x10-1 |
Statistical analysis API access
Experimental data download
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