A Clinical Chemistry phenotypic assay was performed on 1103 mice. The charts show the results of measuring Glucose in 5 female, 5 male mutants compared to 542 female, 551 male controls. The mutants are for the Dusp4tm1a(EUCOMM)Wtsi allele.
decreased circulating glucose level
Loading data
P-values equal or lower to 10-4 (P < 0.0001) are marked as significant.
Glucose | WTSI | Dusp4tm1a(EUCOMM)Wtsi | homozygote | Early adult | EPD0105_5_C02 | 1.09x10-1 | 3.93x10-7 | 3.93x10-7 |
Dusp4 data charts
GlucoseExperiments performed
Associated phenotype
Zygosity
homozygote
Testing protocol
Measured value
Glucose
Testing environment
Lab conditions and equipment
Life stage
Early adult
Background Strain
involves: C57BL/6N
Phenotyping center
WTSI
* The high throughput nature of the IMPC means that large control sample sizes may accumulate over a long period of time. See the animal welfare guidelines for more information.
Glucose / Box plot
Glucose / Scatter plot
Results of statistical analysis
Genotype P value
3.93x10-7
Genotype*Female P value
3.93x10-7
Genotype*Male P value
1.09x10-1
Classification
Overally significant [level = 1e-04 , pvalue = 3.9281473263042e-07 ]; and with phenotype threshold value 1e-04 - females only
Summary statistics of all data in the dataset
Statistical method
Batch effect significant | true |
Variance significant | true |
Genotype*Sex interaction effect p value | 3.93x10-7 |
Genotype parameter estimate | 3.056 |
Genotype standard error estimate | 1.872 |
Genotype Effect P Value | 3.93x10-7 |
Sex Parameter Estimate | 3.056 |
Sex Standard Error Estimate | 0.438 |
Sex Effect P Value | 3.93x10-7 |
Intercept Estimate | 21.801 |
Intercept Estimate Standard Error | 1.654 |
Sex Male KO P Value | 3.93x10-7 |
Sex Female KO P Value | 3.93x10-7 |
WT Residuals Normality Tests | 1.57x10-2 |
KO Residuals Normality Tests | 2.89x10-1 |
Statistical analysis API access
Experimental data download
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