abnormal freezing behavior

  Loading data
P-values equal or lower to 10-4 (P < 0.0001) are marked as significant.
Difference in Conditioning Post-shock and Conditioning Baseline % FreezingUC DavisDhrs7bem1(IMPC)MbpheterozygoteEarly adultCR113576.26x10-31.29x10-55.67x10-7

Dhrs7b data charts

Difference in Conditioning Post-shock and Conditioning Baseline % Freezing
Combination tested with the lowest p-value of 5.67x10-7
Experiments performed

A Fear Conditioning phenotypic assay was performed on 2328 mice. The charts show the results of measuring Difference in Conditioning Post-shock and Conditioning Baseline % Freezing in 8 female, 8 male mutants compared to 1158 female, 1154 male controls. The mutants are for the Dhrs7bem1(IMPC)Mbp allele.

Associated phenotype
Zygosity
heterozygote
Testing protocol
Measured value
Difference in Conditioning Post-shock and Conditioning Baseline % Freezing
Testing environment
Lab conditions and equipment
Life stage
Early adult
Background Strain
involves: C57BL/6NCrl
Phenotyping center
UC Davis

* The high throughput nature of the IMPC means that large control sample sizes may accumulate over a long period of time. See the animal welfare guidelines for more information.

Difference in Conditioning Post-shock and Conditioning Baseline % Freezing / Box plot
Difference in Conditioning Post-shock and Conditioning Baseline % Freezing / Scatter plot

Results of statistical analysis

Summary statistics of all data in the dataset

Statistical method

Batch effect significant false
Variance significant true
Genotype*Sex interaction effect p value 5.67x10-7
Genotype parameter estimate -1.636
Genotype standard error estimate 2.721
Genotype Effect P Value 5.67x10-7
Sex Parameter Estimate -1.636
Sex Standard Error Estimate 0.703
Sex Effect P Value 5.67x10-7
Intercept Estimate 9.398
Intercept Estimate Standard Error 0.501
Sex Male KO P Value 5.67x10-7
Sex Female KO P Value 5.67x10-7
WT Residuals Normality Tests 9.77x10-32
KO Residuals Normality Tests 4.82x10-2

Windowing parameters

View documentation about soft windowing
Sharpness (k) 0.921
Bandwidth (l)1217

Experimental data download

Download data as:  

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