A Clinical Chemistry phenotypic assay was performed on 2422 mice. The charts show the results of measuring HDL-cholesterol in 6 female, 8 male mutants compared to 1194 female, 1214 male controls. The mutants are for the Dhrs7bem1(IMPC)Mbp allele.
increased circulating HDL cholesterol level
Loading data
P-values equal or lower to 10-4 (P < 0.0001) are marked as significant.
| HDL-cholesterol | UC Davis | Dhrs7bem1(IMPC)Mbp | heterozygote | Early adult | CR11357 | 9.03x10-5 | 2.26x10-1 | 2.26x10-1 | |
Dhrs7b data charts
HDL-cholesterolExperiments performed
Associated phenotype
Zygosity
heterozygote
Testing protocol
Measured value
HDL-cholesterol
Testing environment
Lab conditions and equipment
Life stage
Early adult
Background Strain
involves: C57BL/6NCrl
Phenotyping center
UC Davis
* The high throughput nature of the IMPC means that large control sample sizes may accumulate over a long period of time. See the animal welfare guidelines for more information.
HDL-cholesterol / Box plot
HDL-cholesterol / Scatter plot
Results of statistical analysis
Genotype P value
2.26x10-1
Genotype*Female P value
2.26x10-1
Genotype*Male P value
9.03x10-5
Classification
With phenotype threshold value 1e-04 - Significant for males only
Summary statistics of all data in the dataset
Statistical method
| Batch effect significant | true |
| Variance significant | true |
| Genotype*Sex interaction effect p value | 2.26x10-1 |
| Genotype parameter estimate | 19.605 |
| Genotype standard error estimate | 3.804 |
| Genotype Effect P Value | 2.26x10-1 |
| Sex Parameter Estimate | 19.605 |
| Sex Standard Error Estimate | 1.546 |
| Sex Effect P Value | 2.26x10-1 |
| Intercept Estimate | 44.400 |
| Intercept Estimate Standard Error | 4.370 |
| Sex Male KO P Value | 2.26x10-1 |
| Sex Female KO P Value | 2.26x10-1 |
| WT Residuals Normality Tests | 6.88x10-1 |
| KO Residuals Normality Tests | 2.09x10-1 |
Statistical analysis API access
Experimental data download
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