A Body Composition (DEXA lean/fat) phenotypic assay was performed on 3790 mice. The charts show the results of measuring Bone Mineral Content (excluding skull) in 8 female, 8 male mutants compared to 1890 female, 1884 male controls. The mutants are for the Slc4a10tm1b(KOMP)Wtsi allele.
decreased bone mineral content
Loading data
P-values equal or lower to 10-4 (P < 0.0001) are marked as significant.
Bone Mineral Content (excluding skull) | MRC Harwell | Slc4a10tm1b(KOMP)Wtsi | homozygote | Early adult | H-SLC4a10-G08-TM1B | 8.9x10-3 | 6.33x10-5 | 2.06x10-5 |
Slc4a10 data charts
Bone Mineral Content (excluding skull)Experiments performed
Associated phenotype
Zygosity
homozygote
Testing protocol
Measured value
Bone Mineral Content (excluding skull)
Testing environment
Lab conditions and equipment
Life stage
Early adult
Background Strain
involves: C57BL/6NTac
Phenotyping center
MRC Harwell
* The high throughput nature of the IMPC means that large control sample sizes may accumulate over a long period of time. See the animal welfare guidelines for more information.
Bone Mineral Content (excluding skull) / Box plot
Bone Mineral Content (excluding skull) / Scatter plot
Results of statistical analysis
Genotype P value
2.06x10-5
Genotype*Female P value
6.33x10-5
Genotype*Male P value
8.9x10-3
Classification
With phenotype threshold value 1e-04 - both sexes equally
Summary statistics of all data in the dataset
Statistical method
Batch effect significant | true |
Variance significant | true |
Genotype*Sex interaction effect p value | 2.06x10-5 |
Genotype parameter estimate | -0.029 |
Genotype standard error estimate | 0.010 |
Genotype Effect P Value | 2.06x10-5 |
Sex Parameter Estimate | -0.029 |
Sex Standard Error Estimate | 0.005 |
Sex Effect P Value | 2.06x10-5 |
Intercept Estimate | 0.124 |
Intercept Estimate Standard Error | 0.018 |
Sex Male KO P Value | 2.06x10-5 |
Sex Female KO P Value | 2.06x10-5 |
WT Residuals Normality Tests | 1.32x10-9 |
KO Residuals Normality Tests | 6.41x10-1 |
Statistical analysis API access
Experimental data download
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