A Hematology phenotypic assay was performed on 770 mice. The charts show the results of measuring Hemoglobin in 8 female, 8 male mutants compared to 378 female, 376 male controls. The mutants are for the Slc4a10tm1b(KOMP)Wtsi allele.
increased hemoglobin content
Loading data
P-values equal or lower to 10-4 (P < 0.0001) are marked as significant.
Hemoglobin | MRC Harwell | Slc4a10tm1b(KOMP)Wtsi | homozygote | Early adult | H-SLC4a10-G08-TM1B | 4.25x10-1 | 9.98x10-7 | 9.98x10-7 |
Slc4a10 data charts
HemoglobinExperiments performed
Associated phenotype
Zygosity
homozygote
Testing protocol
Measured value
Hemoglobin
Testing environment
Lab conditions and equipment
Life stage
Early adult
Background Strain
involves: C57BL/6NTac
Phenotyping center
MRC Harwell
* The high throughput nature of the IMPC means that large control sample sizes may accumulate over a long period of time. See the animal welfare guidelines for more information.
Hemoglobin / Box plot
Hemoglobin / Scatter plot
Results of statistical analysis
Genotype P value
9.98x10-7
Genotype*Female P value
9.98x10-7
Genotype*Male P value
4.25x10-1
Classification
Overally significant [level = 1e-04 , pvalue = 9.98211258096404e-07 ]; and with phenotype threshold value 1e-04 - females only
Summary statistics of all data in the dataset
Statistical method
Batch effect significant | true |
Variance significant | true |
Genotype*Sex interaction effect p value | 9.98x10-7 |
Genotype parameter estimate | 0.201 |
Genotype standard error estimate | 0.151 |
Genotype Effect P Value | 9.98x10-7 |
Sex Parameter Estimate | 0.201 |
Sex Standard Error Estimate | 0.072 |
Sex Effect P Value | 9.98x10-7 |
Intercept Estimate | 16.531 |
Intercept Estimate Standard Error | 0.239 |
Sex Male KO P Value | 9.98x10-7 |
Sex Female KO P Value | 9.98x10-7 |
WT Residuals Normality Tests | 7.73x10-2 |
KO Residuals Normality Tests | 1.08x10-1 |
Statistical analysis API access
Experimental data download
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