A Hematology phenotypic assay was performed on 422 mice. The charts show the results of measuring Monocyte differential count in 8 female, 8 male mutants compared to 207 female, 199 male controls. The mutants are for the Usp22tm1b(KOMP)Wtsi allele.
increased monocyte cell number
Loading data
P-values equal or lower to 10-4 (P < 0.0001) are marked as significant.
Monocyte differential count | MRC Harwell | Usp22tm1b(KOMP)Wtsi | heterozygote | Early adult | H-USP22-D11-TM1B | 7.35x10-1 | 2.58x10-6 | 2.7x10-6 |
Usp22 data charts
Monocyte differential countExperiments performed
Associated phenotype
Zygosity
heterozygote
Testing protocol
Measured value
Monocyte differential count
Testing environment
Lab conditions and equipment
Life stage
Early adult
Background Strain
involves: C57BL/6NTac
Phenotyping center
MRC Harwell
* The high throughput nature of the IMPC means that large control sample sizes may accumulate over a long period of time. See the animal welfare guidelines for more information.
Monocyte differential count / Box plot
Monocyte differential count / Scatter plot
Results of statistical analysis
Genotype P value
2.7x10-6
Genotype*Female P value
2.58x10-6
Genotype*Male P value
7.35x10-1
Classification
Overally significant [level = 1e-04 , pvalue = 2.69867681376217e-06 ]; and with phenotype threshold value 1e-04 - females only
Summary statistics of all data in the dataset
Statistical method
Batch effect significant | false |
Variance significant | true |
Genotype*Sex interaction effect p value | 2.7x10-6 |
Genotype parameter estimate | 0.169 |
Genotype standard error estimate | 0.264 |
Genotype Effect P Value | 2.7x10-6 |
Sex Parameter Estimate | 0.169 |
Sex Standard Error Estimate | 0.080 |
Sex Effect P Value | 2.7x10-6 |
Intercept Estimate | 2.301 |
Intercept Estimate Standard Error | 0.056 |
Sex Male KO P Value | 2.7x10-6 |
Sex Female KO P Value | 2.7x10-6 |
WT Residuals Normality Tests | 8.04x10-5 |
KO Residuals Normality Tests | 6.67x10-6 |
Statistical analysis API access
Experimental data download
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