A Acoustic Startle and Pre-pulse Inhibition (PPI) phenotypic assay was performed on 843 mice. The charts show the results of measuring Response amplitude - S in 8 female, 8 male mutants compared to 419 female, 408 male controls. The mutants are for the Bbs4tm1b(EUCOMM)Hmgu allele.
increased startle reflex
Loading data
P-values equal or lower to 10-4 (P < 0.0001) are marked as significant.
Response amplitude - S | JAX | Bbs4tm1b(EUCOMM)Hmgu | heterozygote | Early adult | JR24661 | 6.75x10-5 | 3.19x10-1 | 3.3x10-1 |
Bbs4 data charts
Response amplitude - SExperiments performed
Associated phenotype
Zygosity
heterozygote
Testing protocol
Measured value
Response amplitude - S
Testing environment
Lab conditions and equipment
Life stage
Early adult
Background Strain
involves: C57BL/6NJ
Phenotyping center
JAX
* The high throughput nature of the IMPC means that large control sample sizes may accumulate over a long period of time. See the animal welfare guidelines for more information.
Response amplitude - S / Box plot
Response amplitude - S / Scatter plot
Results of statistical analysis
Genotype P value
3.3x10-1
Genotype*Female P value
3.19x10-1
Genotype*Male P value
6.75x10-5
Classification
With phenotype threshold value 1e-04 - Significant for males only
Summary statistics of all data in the dataset
Statistical method
Batch effect significant | true |
Variance significant | true |
Genotype*Sex interaction effect p value | 3.3x10-1 |
Genotype parameter estimate | 77.293 |
Genotype standard error estimate | 75.278 |
Genotype Effect P Value | 3.3x10-1 |
Sex Parameter Estimate | 77.293 |
Sex Standard Error Estimate | 15.364 |
Sex Effect P Value | 3.3x10-1 |
Intercept Estimate | 348.621 |
Intercept Estimate Standard Error | 19.559 |
Sex Male KO P Value | 3.3x10-1 |
Sex Female KO P Value | 3.3x10-1 |
WT Residuals Normality Tests | 7.4x10-6 |
KO Residuals Normality Tests | 7.57x10-1 |
Statistical analysis API access
Experimental data download
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