A Light-Dark Test phenotypic assay was performed on 4049 mice. The charts show the results of measuring Latency to first transition into dark in 8 female, 6 male mutants compared to 2037 female, 1998 male controls. The mutants are for the Bbs4tm1b(EUCOMM)Hmgu allele.
decreased exploration in new environment
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P-values equal or lower to 10-4 (P < 0.0001) are marked as significant.
Latency to first transition into dark | JAX | Bbs4tm1b(EUCOMM)Hmgu | heterozygote | Early adult | JR24661 | 4.35x10-9 | 5.01x10-1 | 5.01x10-1 |
Bbs4 data charts
Latency to first transition into darkExperiments performed
Associated phenotype
Zygosity
heterozygote
Testing protocol
Measured value
Latency to first transition into dark
Testing environment
Lab conditions and equipment
Life stage
Early adult
Background Strain
involves: C57BL/6NJ
Phenotyping center
JAX
* The high throughput nature of the IMPC means that large control sample sizes may accumulate over a long period of time. See the animal welfare guidelines for more information.
Latency to first transition into dark / Box plot
Latency to first transition into dark / Scatter plot
Results of statistical analysis
Genotype P value
5.01x10-1
Genotype*Female P value
5.01x10-1
Genotype*Male P value
4.35x10-9
Classification
Overally insignificant [level = 1e-04 , pvalue = 0.500775088147427 ]; but with phenotype threshold value 1e-04 - males only
Summary statistics of all data in the dataset
Statistical method
Batch effect significant | true |
Variance significant | true |
Genotype*Sex interaction effect p value | 5.01x10-1 |
Genotype parameter estimate | 41.638 |
Genotype standard error estimate | 48.080 |
Genotype Effect P Value | 5.01x10-1 |
Sex Parameter Estimate | 41.638 |
Sex Standard Error Estimate | 6.202 |
Sex Effect P Value | 5.01x10-1 |
Intercept Estimate | 137.082 |
Intercept Estimate Standard Error | 19.616 |
Sex Male KO P Value | 5.01x10-1 |
Sex Female KO P Value | 5.01x10-1 |
WT Residuals Normality Tests | 2.82x10-54 |
KO Residuals Normality Tests | 2.94x10-1 |
Statistical analysis API access
Experimental data download
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