increased circulating phosphate level

  Loading data
P-values equal or lower to 10-4 (P < 0.0001) are marked as significant.
PhosphorusJAXSec61a2em1(IMPC)JhomozygoteEarly adultJR335922.24x10-51.3x10-22.67x10-5

Sec61a2 data charts

Phosphorus
Combination tested with the lowest p-value of 2.24x10-5
Experiments performed

A Clinical Chemistry phenotypic assay was performed on 2906 mice. The charts show the results of measuring Phosphorus in 6 female, 6 male mutants compared to 1446 female, 1448 male controls. The mutants are for the Sec61a2em1(IMPC)J allele.

Associated phenotype
Zygosity
homozygote
Testing protocol
Measured value
Phosphorus
Testing environment
Lab conditions and equipment
Life stage
Early adult
Background Strain
involves: C57BL/6NJ
Phenotyping center
JAX

* The high throughput nature of the IMPC means that large control sample sizes may accumulate over a long period of time. See the animal welfare guidelines for more information.

Phosphorus / Box plot
Phosphorus / Scatter plot

Results of statistical analysis

Summary statistics of all data in the dataset

Statistical method

Batch effect significant true
Variance significant true
Genotype*Sex interaction effect p value 2.67x10-5
Genotype parameter estimate -0.151
Genotype standard error estimate 0.524
Genotype Effect P Value 2.67x10-5
Sex Parameter Estimate -0.151
Sex Standard Error Estimate 0.046
Sex Effect P Value 2.67x10-5
Intercept Estimate 7.084
Intercept Estimate Standard Error 0.073
Sex Male KO P Value 2.67x10-5
Sex Female KO P Value 2.67x10-5
WT Residuals Normality Tests 2.99x10-19
KO Residuals Normality Tests 5.07x10-1

Windowing parameters

View documentation about soft windowing
Sharpness (k) 0.767
Bandwidth (l)1708

Experimental data download

Download data as:  

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