A Clinical Chemistry phenotypic assay was performed on 2906 mice. The charts show the results of measuring Phosphorus in 6 female, 6 male mutants compared to 1446 female, 1448 male controls. The mutants are for the Sec61a2em1(IMPC)J allele.
increased circulating phosphate level
Loading data
P-values equal or lower to 10-4 (P < 0.0001) are marked as significant.
Phosphorus | JAX | Sec61a2em1(IMPC)J | homozygote | Early adult | JR33592 | 2.24x10-5 | 1.3x10-2 | 2.67x10-5 |
Sec61a2 data charts
PhosphorusExperiments performed
Associated phenotype
Zygosity
homozygote
Testing protocol
Measured value
Phosphorus
Testing environment
Lab conditions and equipment
Life stage
Early adult
Background Strain
involves: C57BL/6NJ
Phenotyping center
JAX
* The high throughput nature of the IMPC means that large control sample sizes may accumulate over a long period of time. See the animal welfare guidelines for more information.
Phosphorus / Box plot
Phosphorus / Scatter plot
Results of statistical analysis
Genotype P value
2.67x10-5
Genotype*Female P value
1.3x10-2
Genotype*Male P value
2.24x10-5
Classification
With phenotype threshold value 1e-04 - both sexes equally
Summary statistics of all data in the dataset
Statistical method
Batch effect significant | true |
Variance significant | true |
Genotype*Sex interaction effect p value | 2.67x10-5 |
Genotype parameter estimate | -0.151 |
Genotype standard error estimate | 0.524 |
Genotype Effect P Value | 2.67x10-5 |
Sex Parameter Estimate | -0.151 |
Sex Standard Error Estimate | 0.046 |
Sex Effect P Value | 2.67x10-5 |
Intercept Estimate | 7.084 |
Intercept Estimate Standard Error | 0.073 |
Sex Male KO P Value | 2.67x10-5 |
Sex Female KO P Value | 2.67x10-5 |
WT Residuals Normality Tests | 2.99x10-19 |
KO Residuals Normality Tests | 5.07x10-1 |
Statistical analysis API access
Experimental data download
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