A Acoustic Startle and Pre-pulse Inhibition (PPI) phenotypic assay was performed on 3881 mice. The charts show the results of measuring Response amplitude - S in 8 female, 4 male mutants compared to 1949 female, 1920 male controls. The mutants are for the Sec61a2em1(IMPC)J allele.
increased startle reflex
Loading data
P-values equal or lower to 10-4 (P < 0.0001) are marked as significant.
Response amplitude - S | JAX | Sec61a2em1(IMPC)J | homozygote | Early adult | JR33592 | 5.21x10-2 | 2.34x10-6 | 2.34x10-6 |
Sec61a2 data charts
Response amplitude - SExperiments performed
Associated phenotype
Zygosity
homozygote
Testing protocol
Measured value
Response amplitude - S
Testing environment
Lab conditions and equipment
Life stage
Early adult
Background Strain
involves: C57BL/6NJ
Phenotyping center
JAX
* The high throughput nature of the IMPC means that large control sample sizes may accumulate over a long period of time. See the animal welfare guidelines for more information.
Response amplitude - S / Box plot
Response amplitude - S / Scatter plot
Results of statistical analysis
Genotype P value
2.34x10-6
Genotype*Female P value
2.34x10-6
Genotype*Male P value
5.21x10-2
Classification
Overally significant [level = 1e-04 , pvalue = 2.34164468615461e-06 ]; and with phenotype threshold value 1e-04 - females only
Summary statistics of all data in the dataset
Statistical method
Batch effect significant | true |
Variance significant | true |
Genotype*Sex interaction effect p value | 2.34x10-6 |
Genotype parameter estimate | 197.037 |
Genotype standard error estimate | 182.543 |
Genotype Effect P Value | 2.34x10-6 |
Sex Parameter Estimate | 197.037 |
Sex Standard Error Estimate | 29.189 |
Sex Effect P Value | 2.34x10-6 |
Intercept Estimate | 313.913 |
Intercept Estimate Standard Error | 91.575 |
Sex Male KO P Value | 2.34x10-6 |
Sex Female KO P Value | 2.34x10-6 |
WT Residuals Normality Tests | 1.43x10-21 |
KO Residuals Normality Tests | 2.65x10-3 |
Statistical analysis API access
Experimental data download
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