increased startle reflex

  Loading data
P-values equal or lower to 10-4 (P < 0.0001) are marked as significant.
Response amplitude - SJAXSec61a2em1(IMPC)JhomozygoteEarly adultJR335925.21x10-22.34x10-62.34x10-6

Sec61a2 data charts

Response amplitude - S
Combination tested with the lowest p-value of 2.34x10-6
Experiments performed

A Acoustic Startle and Pre-pulse Inhibition (PPI) phenotypic assay was performed on 3881 mice. The charts show the results of measuring Response amplitude - S in 8 female, 4 male mutants compared to 1949 female, 1920 male controls. The mutants are for the Sec61a2em1(IMPC)J allele.

Associated phenotype
Zygosity
homozygote
Testing protocol
Measured value
Response amplitude - S
Testing environment
Lab conditions and equipment
Life stage
Early adult
Background Strain
involves: C57BL/6NJ
Phenotyping center
JAX

* The high throughput nature of the IMPC means that large control sample sizes may accumulate over a long period of time. See the animal welfare guidelines for more information.

Response amplitude - S / Box plot
Response amplitude - S / Scatter plot

Results of statistical analysis

Summary statistics of all data in the dataset

Statistical method

Batch effect significant true
Variance significant true
Genotype*Sex interaction effect p value 2.34x10-6
Genotype parameter estimate 197.037
Genotype standard error estimate 182.543
Genotype Effect P Value 2.34x10-6
Sex Parameter Estimate 197.037
Sex Standard Error Estimate 29.189
Sex Effect P Value 2.34x10-6
Intercept Estimate 313.913
Intercept Estimate Standard Error 91.575
Sex Male KO P Value 2.34x10-6
Sex Female KO P Value 2.34x10-6
WT Residuals Normality Tests 1.43x10-21
KO Residuals Normality Tests 2.65x10-3

Windowing parameters

View documentation about soft windowing
Sharpness (k) 0.565
Bandwidth (l)1435

Experimental data download

Download data as:  

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