A Clinical Chemistry phenotypic assay was performed on 1321 mice. The charts show the results of measuring Phosphorus in 8 female, 8 male mutants compared to 654 female, 651 male controls. The mutants are for the Irx6tm1b(KOMP)Mbp allele.
increased circulating phosphate level
Loading data
P-values equal or lower to 10-4 (P < 0.0001) are marked as significant.
Phosphorus | KMPC | Irx6tm1b(KOMP)Mbp | homozygote | Early adult | M0045-Irx6 | 3.2x10-6 | 2.96x10-3 | 2.96x10-3 |
Irx6 data charts
PhosphorusExperiments performed
Associated phenotype
Zygosity
homozygote
Testing protocol
Measured value
Phosphorus
Testing environment
Lab conditions and equipment
Life stage
Early adult
Background Strain
involves: C57BL/6NTac
Phenotyping center
KMPC
* The high throughput nature of the IMPC means that large control sample sizes may accumulate over a long period of time. See the animal welfare guidelines for more information.
Phosphorus / Box plot
Phosphorus / Scatter plot
Results of statistical analysis
Genotype P value
2.96x10-3
Genotype*Female P value
2.96x10-3
Genotype*Male P value
3.2x10-6
Classification
Overally insignificant [level = 1e-04 , pvalue = 0.00296233034689686 ]; but with phenotype threshold value 1e-04 - different size as males greater
Summary statistics of all data in the dataset
Statistical method
Batch effect significant | true |
Variance significant | true |
Genotype*Sex interaction effect p value | 2.96x10-3 |
Genotype parameter estimate | -0.010 |
Genotype standard error estimate | 0.389 |
Genotype Effect P Value | 2.96x10-3 |
Sex Parameter Estimate | -0.010 |
Sex Standard Error Estimate | 0.093 |
Sex Effect P Value | 2.96x10-3 |
Intercept Estimate | 7.538 |
Intercept Estimate Standard Error | 0.298 |
Sex Male KO P Value | 2.96x10-3 |
Sex Female KO P Value | 2.96x10-3 |
WT Residuals Normality Tests | 3.44x10-19 |
KO Residuals Normality Tests | 7.78x10-1 |
Statistical analysis API access
Experimental data download
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