A Open Field phenotypic assay was performed on 4786 mice. The charts show the results of measuring Latency to center entry in 8 female, 8 male mutants compared to 2388 female, 2382 male controls. The mutants are for the Usp54tm1b(KOMP)Wtsi allele.
decreased exploration in new environment
Loading data
P-values equal or lower to 10-4 (P < 0.0001) are marked as significant.
Latency to center entry | MRC Harwell | Usp54tm1b(KOMP)Wtsi | homozygote | Early adult | H-USP54-B10-TM1B | 5.16x10-2 | 5.58x10-5 | 5.58x10-5 |
Usp54 data charts
Latency to center entryExperiments performed
Associated phenotype
Zygosity
homozygote
Testing protocol
Measured value
Latency to center entry
Testing environment
Lab conditions and equipment
Life stage
Early adult
Background Strain
involves: C57BL/6NTac
Phenotyping center
MRC Harwell
* The high throughput nature of the IMPC means that large control sample sizes may accumulate over a long period of time. See the animal welfare guidelines for more information.
Latency to center entry / Box plot
Latency to center entry / Scatter plot
Results of statistical analysis
Genotype P value
5.58x10-5
Genotype*Female P value
5.58x10-5
Genotype*Male P value
5.16x10-2
Classification
Overally significant [level = 1e-04 , pvalue = 5.5794884954885e-05 ]; and with phenotype threshold value 1e-04 - females only
Summary statistics of all data in the dataset
Statistical method
Batch effect significant | true |
Variance significant | true |
Genotype*Sex interaction effect p value | 5.58x10-5 |
Genotype parameter estimate | -14.472 |
Genotype standard error estimate | 43.589 |
Genotype Effect P Value | 5.58x10-5 |
Sex Parameter Estimate | -14.472 |
Sex Standard Error Estimate | 10.690 |
Sex Effect P Value | 5.58x10-5 |
Intercept Estimate | -1.730 |
Intercept Estimate Standard Error | 38.347 |
Sex Male KO P Value | 5.58x10-5 |
Sex Female KO P Value | 5.58x10-5 |
WT Residuals Normality Tests | 5.8x10-41 |
KO Residuals Normality Tests | 7.19x10-3 |
Statistical analysis API access
Experimental data download
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