decreased exploration in new environment

  Loading data
P-values equal or lower to 10-4 (P < 0.0001) are marked as significant.
Latency to center entryMRC HarwellUsp54tm1b(KOMP)WtsihomozygoteEarly adultH-USP54-B10-TM1B5.16x10-25.58x10-55.58x10-5

Usp54 data charts

Latency to center entry
Combination tested with the lowest p-value of 5.58x10-5
Experiments performed

A Open Field phenotypic assay was performed on 4786 mice. The charts show the results of measuring Latency to center entry in 8 female, 8 male mutants compared to 2388 female, 2382 male controls. The mutants are for the Usp54tm1b(KOMP)Wtsi allele.

Associated phenotype
Zygosity
homozygote
Testing protocol
Measured value
Latency to center entry
Testing environment
Lab conditions and equipment
Life stage
Early adult
Background Strain
involves: C57BL/6NTac
Phenotyping center
MRC Harwell

* The high throughput nature of the IMPC means that large control sample sizes may accumulate over a long period of time. See the animal welfare guidelines for more information.

Latency to center entry / Box plot
Latency to center entry / Scatter plot

Results of statistical analysis

Summary statistics of all data in the dataset

Statistical method

Batch effect significant true
Variance significant true
Genotype*Sex interaction effect p value 5.58x10-5
Genotype parameter estimate -14.472
Genotype standard error estimate 43.589
Genotype Effect P Value 5.58x10-5
Sex Parameter Estimate -14.472
Sex Standard Error Estimate 10.690
Sex Effect P Value 5.58x10-5
Intercept Estimate -1.730
Intercept Estimate Standard Error 38.347
Sex Male KO P Value 5.58x10-5
Sex Female KO P Value 5.58x10-5
WT Residuals Normality Tests 5.8x10-41
KO Residuals Normality Tests 7.19x10-3

Windowing parameters

View documentation about soft windowing
Sharpness (k) 2.770
Bandwidth (l)484

Experimental data download

Download data as:  

The IMPC Newsletter

Get highlights of the most important data releases, news and events, delivered straight to your email inbox

Subscribe to newsletter