increased neutrophil cell number

  Loading data
P-values equal or lower to 10-4 (P < 0.0001) are marked as significant.
Neutrophil cell countMRC HarwellUsp54tm1b(KOMP)WtsihomozygoteEarly adultH-USP54-B10-TM1B8.97x10-176.85x10-16.78x10-1
Neutrophil differential countMRC HarwellUsp54tm1b(KOMP)WtsihomozygoteEarly adultH-USP54-B10-TM1B1.78x10-217.03x10-17.07x10-1

Usp54 data charts

Neutrophil cell count
Combination tested with the lowest p-value of 8.97x10-17
Experiments performed

A Hematology phenotypic assay was performed on 210 mice. The charts show the results of measuring Neutrophil cell count in 8 female, 8 male mutants compared to 97 female, 97 male controls. The mutants are for the Usp54tm1b(KOMP)Wtsi allele.

Associated phenotype
Zygosity
homozygote
Testing protocol
Measured value
Neutrophil cell count
Testing environment
Lab conditions and equipment
Life stage
Early adult
Background Strain
involves: C57BL/6NTac
Phenotyping center
MRC Harwell

* The high throughput nature of the IMPC means that large control sample sizes may accumulate over a long period of time. See the animal welfare guidelines for more information.

Neutrophil cell count / Box plot
Neutrophil cell count / Scatter plot

Results of statistical analysis

Summary statistics of all data in the dataset

Statistical method

Batch effect significant false
Variance significant true
Genotype*Sex interaction effect p value 6.78x10-1
Genotype parameter estimate 0.389
Genotype standard error estimate 0.231
Genotype Effect P Value 6.78x10-1
Sex Parameter Estimate 0.389
Sex Standard Error Estimate 0.093
Sex Effect P Value 6.78x10-1
Intercept Estimate 0.593
Intercept Estimate Standard Error 0.067
Sex Male KO P Value 6.78x10-1
Sex Female KO P Value 6.78x10-1
WT Residuals Normality Tests 2.14x10-15
KO Residuals Normality Tests 1.83x10-3

Windowing parameters

View documentation about soft windowing
Sharpness (k) 3.997
Bandwidth (l)94

Experimental data download

Download data as:  

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