A Hematology phenotypic assay was performed on 210 mice. The charts show the results of measuring Neutrophil cell count in 8 female, 8 male mutants compared to 97 female, 97 male controls. The mutants are for the Usp54tm1b(KOMP)Wtsi allele.
increased neutrophil cell number
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P-values equal or lower to 10-4 (P < 0.0001) are marked as significant.
Neutrophil cell count | MRC Harwell | Usp54tm1b(KOMP)Wtsi | homozygote | Early adult | H-USP54-B10-TM1B | 8.97x10-17 | 6.85x10-1 | 6.78x10-1 | |
Neutrophil differential count | MRC Harwell | Usp54tm1b(KOMP)Wtsi | homozygote | Early adult | H-USP54-B10-TM1B | 1.78x10-21 | 7.03x10-1 | 7.07x10-1 |
Usp54 data charts
Neutrophil cell countExperiments performed
Associated phenotype
Zygosity
homozygote
Testing protocol
Measured value
Neutrophil cell count
Testing environment
Lab conditions and equipment
Life stage
Early adult
Background Strain
involves: C57BL/6NTac
Phenotyping center
MRC Harwell
* The high throughput nature of the IMPC means that large control sample sizes may accumulate over a long period of time. See the animal welfare guidelines for more information.
Neutrophil cell count / Box plot
Neutrophil cell count / Scatter plot
Results of statistical analysis
Genotype P value
6.78x10-1
Genotype*Female P value
6.85x10-1
Genotype*Male P value
8.97x10-17
Classification
Overally insignificant [level = 1e-04 , pvalue = 0.67833840303047 ]; but with phenotype threshold value 1e-04 - males only
Summary statistics of all data in the dataset
Statistical method
Batch effect significant | false |
Variance significant | true |
Genotype*Sex interaction effect p value | 6.78x10-1 |
Genotype parameter estimate | 0.389 |
Genotype standard error estimate | 0.231 |
Genotype Effect P Value | 6.78x10-1 |
Sex Parameter Estimate | 0.389 |
Sex Standard Error Estimate | 0.093 |
Sex Effect P Value | 6.78x10-1 |
Intercept Estimate | 0.593 |
Intercept Estimate Standard Error | 0.067 |
Sex Male KO P Value | 6.78x10-1 |
Sex Female KO P Value | 6.78x10-1 |
WT Residuals Normality Tests | 2.14x10-15 |
KO Residuals Normality Tests | 1.83x10-3 |
Statistical analysis API access
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