A Clinical Chemistry phenotypic assay was performed on 2542 mice. The charts show the results of measuring Urea (Blood Urea Nitrogen - BUN) in 8 female, 6 male mutants compared to 1256 female, 1272 male controls. The mutants are for the Lsm8em1(IMPC)Mbp allele.
increased blood urea nitrogen level
Loading data
P-values equal or lower to 10-4 (P < 0.0001) are marked as significant.
Urea (Blood Urea Nitrogen - BUN) | UC Davis | Lsm8em1(IMPC)Mbp | heterozygote | Early adult | CR10201 | 3.7x10-1 | 3.18x10-6 | 2.93x10-6 |
Lsm8 data charts
Urea (Blood Urea Nitrogen - BUN)Experiments performed
Associated phenotype
Zygosity
heterozygote
Testing protocol
Measured value
Urea (Blood Urea Nitrogen - BUN)
Testing environment
Lab conditions and equipment
Life stage
Early adult
Background Strain
involves: C57BL/6NCrl
Phenotyping center
UC Davis
* The high throughput nature of the IMPC means that large control sample sizes may accumulate over a long period of time. See the animal welfare guidelines for more information.
Urea (Blood Urea Nitrogen - BUN) / Box plot
Urea (Blood Urea Nitrogen - BUN) / Scatter plot
Results of statistical analysis
Genotype P value
2.93x10-6
Genotype*Female P value
3.18x10-6
Genotype*Male P value
3.7x10-1
Classification
Overally significant [level = 1e-04 , pvalue = 2.92907517862595e-06 ]; and with phenotype threshold value 1e-04 - females only
Summary statistics of all data in the dataset
Statistical method
Batch effect significant | true |
Variance significant | true |
Genotype*Sex interaction effect p value | 2.93x10-6 |
Genotype parameter estimate | 0.766 |
Genotype standard error estimate | 1.655 |
Genotype Effect P Value | 2.93x10-6 |
Sex Parameter Estimate | 0.766 |
Sex Standard Error Estimate | 0.267 |
Sex Effect P Value | 2.93x10-6 |
Intercept Estimate | 21.909 |
Intercept Estimate Standard Error | 0.247 |
Sex Male KO P Value | 2.93x10-6 |
Sex Female KO P Value | 2.93x10-6 |
WT Residuals Normality Tests | 1.86x10-13 |
KO Residuals Normality Tests | 3.39x10-1 |
Statistical analysis API access
Experimental data download
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