A Clinical Chemistry phenotypic assay was performed on 2514 mice. The charts show the results of measuring Creatinine in 7 female, 4 male mutants compared to 1250 female, 1253 male controls. The mutants are for the Lsm8em1(IMPC)Mbp allele.
increased circulating creatinine level
Loading data
P-values equal or lower to 10-4 (P < 0.0001) are marked as significant.
Creatinine | UC Davis | Lsm8em1(IMPC)Mbp | heterozygote | Early adult | CR10201 | 1.37x10-1 | 2.64x10-10 | 2.64x10-10 |
Lsm8 data charts
CreatinineExperiments performed
Associated phenotype
Zygosity
heterozygote
Testing protocol
Measured value
Creatinine
Testing environment
Lab conditions and equipment
Life stage
Early adult
Background Strain
involves: C57BL/6NCrl
Phenotyping center
UC Davis
* The high throughput nature of the IMPC means that large control sample sizes may accumulate over a long period of time. See the animal welfare guidelines for more information.
Creatinine / Box plot
Creatinine / Scatter plot
Results of statistical analysis
Genotype P value
2.64x10-10
Genotype*Female P value
2.64x10-10
Genotype*Male P value
1.37x10-1
Classification
Overally significant [level = 1e-04 , pvalue = 2.64192001608876e-10 ]; and with phenotype threshold value 1e-04 - females only
Summary statistics of all data in the dataset
Statistical method
Batch effect significant | true |
Variance significant | true |
Genotype*Sex interaction effect p value | 2.64x10-10 |
Genotype parameter estimate | -0.016 |
Genotype standard error estimate | 0.015 |
Genotype Effect P Value | 2.64x10-10 |
Sex Parameter Estimate | -0.016 |
Sex Standard Error Estimate | 0.003 |
Sex Effect P Value | 2.64x10-10 |
Intercept Estimate | 0.196 |
Intercept Estimate Standard Error | 0.009 |
Sex Male KO P Value | 2.64x10-10 |
Sex Female KO P Value | 2.64x10-10 |
WT Residuals Normality Tests | 2.82x10-24 |
KO Residuals Normality Tests | 1.5x10-1 |
Statistical analysis API access
Experimental data download
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