increased circulating alanine transaminase level

  Loading data
P-values equal or lower to 10-4 (P < 0.0001) are marked as significant.
Alanine aminotransferaseUC DavisLsm8em1(IMPC)MbpheterozygoteEarly adultCR102019.17x10-16.92x10-398.03x10-39

Lsm8 data charts

Alanine aminotransferase
Combination tested with the lowest p-value of 6.92x10-39
Experiments performed

A Clinical Chemistry phenotypic assay was performed on 2537 mice. The charts show the results of measuring Alanine aminotransferase in 8 female, 6 male mutants compared to 1256 female, 1267 male controls. The mutants are for the Lsm8em1(IMPC)Mbp allele.

Associated phenotype
Zygosity
heterozygote
Testing protocol
Measured value
Alanine aminotransferase
Testing environment
Lab conditions and equipment
Life stage
Early adult
Background Strain
involves: C57BL/6NCrl
Phenotyping center
UC Davis

* The high throughput nature of the IMPC means that large control sample sizes may accumulate over a long period of time. See the animal welfare guidelines for more information.

Alanine aminotransferase / Box plot
Alanine aminotransferase / Scatter plot

Results of statistical analysis

Summary statistics of all data in the dataset

Statistical method

Batch effect significant false
Variance significant true
Genotype*Sex interaction effect p value 8.03x10-39
Genotype parameter estimate 2.869
Genotype standard error estimate 24.043
Genotype Effect P Value 8.03x10-39
Sex Parameter Estimate 2.869
Sex Standard Error Estimate 4.636
Sex Effect P Value 8.03x10-39
Intercept Estimate 37.913
Intercept Estimate Standard Error 3.300
Sex Male KO P Value 8.03x10-39
Sex Female KO P Value 8.03x10-39
WT Residuals Normality Tests 1.64x10-49
KO Residuals Normality Tests 3.72x10-4

Windowing parameters

View documentation about soft windowing
Sharpness (k) 2.770
Bandwidth (l)343

Experimental data download

Download data as:  

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