A Echo phenotypic assay was performed on 1995 mice. The charts show the results of measuring LVIDs in 8 female, 8 male mutants compared to 984 female, 995 male controls. The mutants are for the Aoc1tm1b(EUCOMM)Hmgu allele.
abnormal heart left ventricle morphology
Loading data
P-values equal or lower to 10-4 (P < 0.0001) are marked as significant.
LVIDs | HMGU | Aoc1tm1b(EUCOMM)Hmgu | homozygote | Early adult | H4340-HEPD0615_1_A11-1 | 1.16x10-4 | 3.95x10-3 | 1.54x10-5 |
Aoc1 data charts
LVIDsExperiments performed
Associated phenotype
Zygosity
homozygote
Testing protocol
Measured value
LVIDs
Testing environment
Lab conditions and equipment
Life stage
Early adult
Background Strain
involves: C57BL/6NTac
Phenotyping center
HMGU
* The high throughput nature of the IMPC means that large control sample sizes may accumulate over a long period of time. See the animal welfare guidelines for more information.
LVIDs / Box plot
LVIDs / Scatter plot
Results of statistical analysis
Genotype P value
1.54x10-5
Genotype*Female P value
3.95x10-3
Genotype*Male P value
1.16x10-4
Classification
With phenotype threshold value 1e-04 - both sexes equally
Summary statistics of all data in the dataset
Statistical method
Batch effect significant | true |
Variance significant | true |
Genotype*Sex interaction effect p value | 1.54x10-5 |
Genotype parameter estimate | -0.056 |
Genotype standard error estimate | 0.081 |
Genotype Effect P Value | 1.54x10-5 |
Sex Parameter Estimate | -0.056 |
Sex Standard Error Estimate | 0.036 |
Sex Effect P Value | 1.54x10-5 |
Intercept Estimate | 0.200 |
Intercept Estimate Standard Error | 0.139 |
Sex Male KO P Value | 1.54x10-5 |
Sex Female KO P Value | 1.54x10-5 |
WT Residuals Normality Tests | 1.59x10-12 |
KO Residuals Normality Tests | 9.94x10-1 |
Statistical analysis API access
Experimental data download
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