abnormal heart left ventricle morphology

  Loading data
P-values equal or lower to 10-4 (P < 0.0001) are marked as significant.
LVIDsHMGUAoc1tm1b(EUCOMM)HmguhomozygoteEarly adultH4340-HEPD0615_1_A11-11.16x10-43.95x10-31.54x10-5

Aoc1 data charts

LVIDs
Combination tested with the lowest p-value of 1.54x10-5
Experiments performed

A Echo phenotypic assay was performed on 1995 mice. The charts show the results of measuring LVIDs in 8 female, 8 male mutants compared to 984 female, 995 male controls. The mutants are for the Aoc1tm1b(EUCOMM)Hmgu allele.

Associated phenotype
Zygosity
homozygote
Testing protocol
Measured value
LVIDs
Testing environment
Lab conditions and equipment
Life stage
Early adult
Background Strain
involves: C57BL/6NTac
Phenotyping center
HMGU

* The high throughput nature of the IMPC means that large control sample sizes may accumulate over a long period of time. See the animal welfare guidelines for more information.

LVIDs / Box plot
LVIDs / Scatter plot

Results of statistical analysis

Summary statistics of all data in the dataset

Statistical method

Batch effect significant true
Variance significant true
Genotype*Sex interaction effect p value 1.54x10-5
Genotype parameter estimate -0.056
Genotype standard error estimate 0.081
Genotype Effect P Value 1.54x10-5
Sex Parameter Estimate -0.056
Sex Standard Error Estimate 0.036
Sex Effect P Value 1.54x10-5
Intercept Estimate 0.200
Intercept Estimate Standard Error 0.139
Sex Male KO P Value 1.54x10-5
Sex Female KO P Value 1.54x10-5
WT Residuals Normality Tests 1.59x10-12
KO Residuals Normality Tests 9.94x10-1

Windowing parameters

View documentation about soft windowing
Sharpness (k) 0.679
Bandwidth (l)124

Experimental data download

Download data as:  

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