A Clinical Chemistry phenotypic assay was performed on 2551 mice. The charts show the results of measuring Aspartate aminotransferase in 7 female, 7 male mutants compared to 1264 female, 1273 male controls. The mutants are for the Mei4em1(IMPC)Mbp allele.
increased circulating aspartate transaminase level
Loading data
P-values equal or lower to 10-4 (P < 0.0001) are marked as significant.
Aspartate aminotransferase | UC Davis | Mei4em1(IMPC)Mbp | homozygote | Early adult | CR10825 | 4.11x10-1 | 2.65x10-6 | 2.65x10-6 |
Mei4 data charts
Aspartate aminotransferaseExperiments performed
Associated phenotype
Zygosity
homozygote
Testing protocol
Measured value
Aspartate aminotransferase
Testing environment
Lab conditions and equipment
Life stage
Early adult
Background Strain
involves: C57BL/6NCrl
Phenotyping center
UC Davis
* The high throughput nature of the IMPC means that large control sample sizes may accumulate over a long period of time. See the animal welfare guidelines for more information.
Aspartate aminotransferase / Box plot
Aspartate aminotransferase / Scatter plot
Results of statistical analysis
Genotype P value
2.65x10-6
Genotype*Female P value
2.65x10-6
Genotype*Male P value
4.11x10-1
Classification
Overally significant [level = 1e-04 , pvalue = 2.65005310084998e-06 ]; and with phenotype threshold value 1e-04 - females only
Summary statistics of all data in the dataset
Statistical method
Batch effect significant | true |
Variance significant | true |
Genotype*Sex interaction effect p value | 2.65x10-6 |
Genotype parameter estimate | -7.727 |
Genotype standard error estimate | 38.771 |
Genotype Effect P Value | 2.65x10-6 |
Sex Parameter Estimate | -7.727 |
Sex Standard Error Estimate | 6.157 |
Sex Effect P Value | 2.65x10-6 |
Intercept Estimate | 215.715 |
Intercept Estimate Standard Error | 17.337 |
Sex Male KO P Value | 2.65x10-6 |
Sex Female KO P Value | 2.65x10-6 |
WT Residuals Normality Tests | 3.09x10-44 |
KO Residuals Normality Tests | 6.81x10-2 |
Statistical analysis API access
Experimental data download
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