A Body Composition (DEXA lean/fat) phenotypic assay was performed on 5203 mice. The charts show the results of measuring Lean/Body weight in 8 female, 8 male mutants compared to 2622 female, 2565 male controls. The mutants are for the Ttc7em1(IMPC)J allele.
decreased lean body mass
Loading data
P-values equal or lower to 10-4 (P < 0.0001) are marked as significant.
Lean/Body weight | JAX | Ttc7em1(IMPC)J | heterozygote | Early adult | JR31993 | 3.15x10-5 | 1.71x10-2 | 1.79x10-2 | |
Lean mass | JAX | Ttc7em1(IMPC)J | heterozygote | Early adult | JR31993 | 2x10-6 | 2.13x10-1 | 2.16x10-1 |
Ttc7 data charts
Lean/Body weightExperiments performed
Associated phenotype
Zygosity
heterozygote
Testing protocol
Measured value
Lean/Body weight
Testing environment
Lab conditions and equipment
Life stage
Early adult
Background Strain
involves: C57BL/6NJ
Phenotyping center
JAX
* The high throughput nature of the IMPC means that large control sample sizes may accumulate over a long period of time. See the animal welfare guidelines for more information.
Lean/Body weight / Box plot
Lean/Body weight / Scatter plot
Results of statistical analysis
Genotype P value
1.79x10-2
Genotype*Female P value
1.71x10-2
Genotype*Male P value
3.15x10-5
Classification
Overally insignificant [level = 1e-04 , pvalue = 0.0179285193516877 ]; but with phenotype threshold value 1e-04 - different size as males greater
Summary statistics of all data in the dataset
Statistical method
Batch effect significant | true |
Variance significant | true |
Genotype*Sex interaction effect p value | 1.79x10-2 |
Genotype parameter estimate | -0.020 |
Genotype standard error estimate | 0.027 |
Genotype Effect P Value | 1.79x10-2 |
Sex Parameter Estimate | -0.020 |
Sex Standard Error Estimate | 0.002 |
Sex Effect P Value | 1.79x10-2 |
Intercept Estimate | 0.832 |
Intercept Estimate Standard Error | 0.002 |
Sex Male KO P Value | 1.79x10-2 |
Sex Female KO P Value | 1.79x10-2 |
WT Residuals Normality Tests | 1.6x10-11 |
KO Residuals Normality Tests | 7.48x10-1 |
Statistical analysis API access
Experimental data download
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