decreased lean body mass

  Loading data
P-values equal or lower to 10-4 (P < 0.0001) are marked as significant.
Lean/Body weightJAXTtc7em1(IMPC)JheterozygoteEarly adultJR319933.15x10-51.71x10-21.79x10-2
Lean massJAXTtc7em1(IMPC)JheterozygoteEarly adultJR319932x10-62.13x10-12.16x10-1

Ttc7 data charts

Lean/Body weight
Combination tested with the lowest p-value of 3.15x10-5
Experiments performed

A Body Composition (DEXA lean/fat) phenotypic assay was performed on 5203 mice. The charts show the results of measuring Lean/Body weight in 8 female, 8 male mutants compared to 2622 female, 2565 male controls. The mutants are for the Ttc7em1(IMPC)J allele.

Associated phenotype
Zygosity
heterozygote
Testing protocol
Measured value
Lean/Body weight
Testing environment
Lab conditions and equipment
Life stage
Early adult
Background Strain
involves: C57BL/6NJ
Phenotyping center
JAX

* The high throughput nature of the IMPC means that large control sample sizes may accumulate over a long period of time. See the animal welfare guidelines for more information.

Lean/Body weight / Box plot
Lean/Body weight / Scatter plot

Results of statistical analysis

Summary statistics of all data in the dataset

Statistical method

Batch effect significant true
Variance significant true
Genotype*Sex interaction effect p value 1.79x10-2
Genotype parameter estimate -0.020
Genotype standard error estimate 0.027
Genotype Effect P Value 1.79x10-2
Sex Parameter Estimate -0.020
Sex Standard Error Estimate 0.002
Sex Effect P Value 1.79x10-2
Intercept Estimate 0.832
Intercept Estimate Standard Error 0.002
Sex Male KO P Value 1.79x10-2
Sex Female KO P Value 1.79x10-2
WT Residuals Normality Tests 1.6x10-11
KO Residuals Normality Tests 7.48x10-1

Windowing parameters

View documentation about soft windowing
Sharpness (k) 3.997
Bandwidth (l)780

Experimental data download

Download data as:  

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