A Lung mechanics by forced oscillations phenotypic assay was performed on 2001 mice. The charts show the results of measuring Esn in 4 female, 2 male mutants compared to 1015 female, 980 male controls. The mutants are for the Ptchd4em1(IMPC)Ccpcz allele.
increased lung elastance
Loading data
P-values equal or lower to 10-4 (P < 0.0001) are marked as significant.
| Esn | CCP-IMG | Ptchd4em1(IMPC)Ccpcz | homozygote | Early adult | CCP-Ptchd4-exdel-EM1-B6N | — | 7.31x10-5 | — | |
Ptchd4 data charts
EsnExperiments performed
Associated phenotype
Zygosity
homozygote
Testing protocol
Measured value
Esn
Testing environment
Lab conditions and equipment
Life stage
Early adult
Background Strain
involves: C57BL/6NCrl
Phenotyping center
CCP-IMG
* The high throughput nature of the IMPC means that large control sample sizes may accumulate over a long period of time. See the animal welfare guidelines for more information.
Esn / Box plot
Esn / Scatter plot
Results of statistical analysis
Genotype P value
7.31x10-5
Genotype*Female P value
N/A
Genotype*Male P value
N/A
Classification
With phenotype threshold value 1e-04 - a significant change for the one sex (female) tested
Summary statistics of all data in the dataset
Statistical method
| Batch effect significant | true |
| Variance significant | true |
| Genotype*Sex interaction effect p value | 7.31x10-5 |
| Genotype parameter estimate | N/A |
| Genotype standard error estimate | 1.737 |
| Genotype Effect P Value | 7.31x10-5 |
| Sex Parameter Estimate | N/A |
| Sex Standard Error Estimate | N/A |
| Sex Effect P Value | 7.31x10-5 |
| Intercept Estimate | 47.111 |
| Intercept Estimate Standard Error | 2.612 |
| Sex Male KO P Value | 7.31x10-5 |
| Sex Female KO P Value | 7.31x10-5 |
| WT Residuals Normality Tests | 2.9x10-7 |
| KO Residuals Normality Tests | 4.68x10-1 |
Statistical analysis API access
Experimental data download
Download data as: